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• Research from University of Tennessee Health Science Center Yields New Data on Molecular Endocrinology
• Researchers from Yonsei University College of Medicine Describe Findings in Medical Science

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Research on Life Science Research Detailed by E. Iglesias-Gutierrez and Co-Authors

2013 JAN 7 (NewsRx) -- By a News Reporter-Staff News Editor at Cardiovascular Week -- Research findings on Life Science Research are discussed in a new report. According to news reporting from Madrid, Spain, by NewsRx journalists, research stated, "Considering that hyperhomocysteinemia is an independent risk factor for cardiovascular disease, the purpose of this study was to determine the kinetics of serum homocysteine (tHcy) and the vitamins involved in its metabolism (folates, B(12), and B(6)) in response to acute exercise at different intensities. Eight sedentary males (18-27 yr) took part in the study."

The news correspondents obtained a quote from the research, "Subjects were required to complete two isocaloric (400 kcal) acute exercise trials on separate occasions at 40% (low intensity, LI) and 80% VO(2peak) (high intensity, HI). Blood samples were drawn at different points before (pre4 and pre0 h), during (exer10, exer20, exer30, exer45, and exer60 min), and after exercise (post0, post3, and post19 h). Dietary, genetic, and lifestyle factors were controlled. Maximum tHcy occurred during exercise, both at LI (8.6 (8.0-10.1) mol/L, 9.3% increase from pre0) and HI (9.4 (8.2-10.6) mol/L, 25.7% increase from pre0), coinciding with an accumulated energy expenditure independent of the exercise intensity. From this point onwards tHcy declined until the cessation of exercise and continued descending. At post19, tHcy was not different from pre-exercise values. No values of hyperhomocysteinemia were observed at any sampling point and intensity."

According to the news reporters, the research concluded: "Acute exercise in sedentary individuals, even at HI, shows no negative effect on tHcy when at least 400 kcal are spent during exercise and the nutritional status for folate, B(12), and B(6) is adequate, since no hyperhomocysteinemia has been observed and basal concentrations were recovered in less than 24 h. This could be relevant for further informing healthy exercise recommendations."

For more information on this research see: Transient Increase in Homocysteine but Not Hyperhomocysteinemia during Acute Exercise at Different Intensities in Sedentary Individuals. Plos One, 2012;7(12):e51185. (Public Library of Science - www.plos.org; Plos One - www.plosone.org)

Our news journalists report that additional information may be obtained by contacting E. Iglesias-Gutierrez, Dept. of Pharmaceutical and Food Sciences, CEU San Pablo University, Madrid, Spain.

Keywords for this news article include: Spain, Madrid, Europe, Genetics, Cardiology, Avitaminosis, Malnutrition, Cardiovascular, Sulfur Amino Acids, Deficiency Diseases, Nutrition Disorders, Hyperhomocysteinemia, Vitamin B Deficiency, Life Science Research, Malabsorption Syndromes, Nutritional and Metabolic Diseases, Inborn Errors Amino Acid Metabolism.

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