Basal Cell Nevus Syndrome
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Scientists at Christchurch Hospital discuss research in kidneys
2009 MAY 11 - (NewsRx.com) -- Investigators publish new data in the report 'Delayed diagnosis of Gorlin's syndrome in a renal transplant recipient.' According to a study from Christchurch, New Zealand, "A 35-year-old woman was referred to the dedicated dermatology clinic for RTR. She underwent her first renal transplant at 18 years of age due to chronic renal failure following reflux nephropathy of the single right kidney (left kidney agenesis)." "She has since then had two further transplants. During clinical examination she was noted to have at least 16 basal cell carcinomas (BCC) and there are records in the case notes of 10 BCC having being excised and confirmed histologically in the past. By contrast, she had only had two squamous cell carcinomas (SCC) excised. She was also noted to have distinctive facial features, a kyphoscoliosis and palmar pits, and a diagnosis of Gorlin's (naevoid BCC) syndrome (GS) was made," wrote K.A. Mackenzie and colleagues, Christchurch Hospital. The researchers concluded: "Although immunosuppression may have contributed to the multiplicity of her BCC, the contrasting very small number of SCC is unusual in an organ transplant recipient and this alerted the authors to the diagnosis of GS." Mackenzie and colleagues published the results of their research in Australasian Journal of Dermatology (Delayed diagnosis of Gorlin's syndrome in a renal transplant recipient. Australasian Journal of Dermatology, 2009;50(2):121-4). For additional information, contact K.A. Mackenzie, Christchurch Hospital, Departments of Plastic and Reconstructive Surgery, Christchurch, New Zealand. The publisher of the Australasian Journal of Dermatology can be contacted at: Blackwell Publishing Inc., 350 Main St., Malden, MA 02148, USA. Keywords: New Zealand, Christchurch, Kidneys, Basal Cell Cancer, Basal Cell Carcinoma, Basal Cell Nevus Syndrome, Chronic Kidney Failure, Chronic Renal Failure, Dermatology, Kidney, Kidney Transplant, Nephrology, Oncology, Organ Transplant, Reflux Nephropathy, Renal Allograft, Renal Failure, Renal Transplant. This article was prepared by Clinical Oncology Week editors from staff and other reports. Copyright 2009, Clinical Oncology Week via NewsRx.com.
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