Beta Thalassemia

Data on thalassemia described by S. Kumar et al

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"The CBC showed microcytic hypochromic anemia. The HPLC and CBC suggested the possibility of compound heterozygote state for HbC/beta-thalassemia. The alkali and acid electrophoresis findings were consistent with the above diagnosis. The DNA analysis confirmed compound heterozygote state for HbC/beta(0)-thalassemia (Fr 8/9 mutation). The studies on the parents showed that mother was a compound heterozygote for HbD(Punjab) and HbC while father had beta-thalassemia trait. To the best of our knowledge, this is the first confirmed report of HbC from India," wrote S. Kumar and colleagues.

The researchers concluded: "The paper discusses the hematological findings in this subject and her mother (a compound heterozygote for HbD(Punjab) and HbC)."

Kumar and colleagues published their study in International Journal of Laboratory Hematology (Case report of HbC/beta(0)-thalassemia from india. International Journal of Laboratory Hematology, 2007;29(5):381-385).

For additional information, contact S.K. Sood, Sir Ganga Ram Hospital, Dept. of Hematology, Rajinder Nagar, New Delhi, India.

Publisher contact information for the International Journal of Laboratory Hematology is: Blackwell Publishing, 9600 Garsington Rd., Oxford OX4 2DQ, Oxon, England.

Keywords: India, New Delhi, Hematology, Thalassemia.

This article was prepared by Hematology Week editors from staff and other reports. Copyright 2007, Hematology Week via NewsRx.com.