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Reports outline DNA research study findings from Hong Kong University of Science & Technology
2009 JUL 6 - (NewsRx.com) -- According to a study from Hong Kong, People's Republic of China, "A user-friendly software system, UNIQUIMER 3D, was developed to design DNA structures for nanotechnology applications. It consists of 3D visualization, internal energy minimization, sequence generation and construction of motif array simulations (2D tiles and 3D lattices) functionalities." "The system can be used to check structural deformation and design errors under scaled-up conditions. UNIQUIMER 3D has been tested on the design of both existing motifs (holiday junction, 4 4 tile, double crossover, DNA tetrahedron, DNA cube, etc.) and nonexisting motifs (soccer ball). The results demonstrated UNIQUIMER 3Ds capability in designing large complex structures. We also designed a de novo sequence generation algorithm," wrote J.H. Zhu and colleagues, Hong Kong University of Science & Technology. The researchers concluded: "UNIQUIMER 3D was developed for the Windows environment and is provided free of charge to the nonprofit research institutions." Zhu and colleagues published their study in Nucleic Acids Research (UNIQUIMER 3D, a software system for structural DNA nanotechnology design, analysis and evaluation. Nucleic Acids Research, 2009;37(7):2164-2175). For more information, contact Y.L. Mi, Hong Kong University of Science & Technology, Dept. of Chemical & Biomolecular Engineering, Hong Kong, Hong Kong, People's Republic of China. Publisher contact information for the journal Nucleic Acids Research is: Oxford University Press, Great Clarendon St., Oxford OX2 6DP, England. Keywords: People's Republic of China, Hong Kong, DNA Research, DNA, Hong Kong University of Science & Technology. This article was prepared by Proteomics Weekly editors from staff and other reports. Copyright 2009, Proteomics Weekly via NewsRx.com.
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