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New antimicrobials study findings have been reported by scientists at Gazi University
2009 MAY 25 - (NewsRx.com) -- According to a study from Ankara, Turkey, "The sulfonamide functional group has aroused interest in both medicinal and bioorganic chemistry." "In this study, some new phenylselanyl-1-(toluene-4-sulfonyl)-1H-tetrazole derivatives (2a-f) have been synthesized using dicyclohexylcarbodiimide/dimethylaminopyridine (DCC/DMAP). The structures of the presently synthesized compounds were elucidated by spectroscopic methods [Fourier-transform infrared (FTIR) spectroscopy, H-1 nuclear magnetic resonance (NMR), C-13 nuclear magnetic resonance-attached proton test (C-13 NMR-APT), and mass spectrometry (MS)]," wrote Y. Yildirir and colleagues, Gazi University. The researchers concluded: "In addition, the antimicrobial activity of the synthesized compounds and two antibiotics [sulfamethoxazole (SMX) and sulfamerazine (SRZ)] were investigated against some microorganisms." Yildirir and colleagues published their study in Medicinal Chemistry Research (The synthesis and investigation of the antimicrobial activity of some new phenylselanyl-1-(Toluene-4sulfonyl)-1H-tetrazole derivatives. Medicinal Chemistry Research, 2009;18(2):91-97). For more information, contact Y. Yildirir, Gazi University, Dept. of Chemical, Faculty Science & Arts, TR-06500 Ankara, Turkey. Publisher contact information for the journal Medicinal Chemistry Research is: Birkhauser Boston Inc., 675 Massachusetts Avenue, Cambridge, MA 02139, USA. Keywords: Turkey, Ankara, Antimicrobial, Antimicrobials, Bioorganic Chemistry, Medicinal Chemistry, Gazi University. This article was prepared by Anti-Infectives Week editors from staff and other reports. Copyright 2009, Anti-Infectives Week via NewsRx.com.
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