Research from Meir Medical Center, Department of Urology has provided new data on bladder cancer
2007 NOV 19 -- Investigators publish new data in the report 'Urological implications of concurrent bladder and lung cancer.' According to a study from Kfar Saba, Israel, "Multiple primary malignancies are increasingly being detected among cancer patients To investigate the co-occurrence of primary bladder cancer and primary lung cancer, two established smoking-related neoplasms characteristically associated with increased risk of secondary cancers A retrospective search of the patient registry in our institution identified 25 patients (23 men and 2 women) who were diagnosed with both bladder cancer and lung cancer during the period 1990-2005. Medical records were reviewed and clinical and pathological data were extracted In 21 patients (84%) bladder cancer was the first primary tumor and in 4 (16%) the second primary tumor." "More than 90% of the patients had a history of smoking. Mean smoking exposure was 62.1 pack years (range 30-120). All bladder cancers were transitional cell carcinomas with the majority being superficial at presentation. Most lung cancers were of the non-small cell type. Second primary lung cancers were significantly more advanced at diagnosis. Overall, mean follow-up was 105.8 months (range 6-288). Seven patients (28%) were alive at the time of evaluation; 68% died of lung cancer, while none died of bladder cancer Second primary lung cancer may occur in patients with bladder carcinoma and vice versa," wrote M. Vainrib and colleagues, Meir Medical Center, Department of Urology. The researchers concluded: "In view of the relatively frequent involvement of the genitourinary tract as a site of multiple primary tumors, urologists may have a key role in the detection of second primary tumors arising in the genitourinary tract, or second primary tumors that occur in patients with primary genitourinary tract malignancies." Vainrib and colleagues published their study in Israel Medical Association Journal (Urological implications of concurrent bladder and lung cancer. Israel Medical Association Journal, 2007;9(10):732-5). For more information, contact M. Vainrib, Meir Medical Center, Dept. of Urology, Kfar Saba, Israel. Publisher contact information for the Israel Medical Association Journal is: Israel Medical Association Journal, 2 Twin Towers, 11TH FL, 35 Jabotinsky St., PO Box 3604, Ramat GaN 52136, Israel. Keywords: Israel, Kfar Saba, Bladder Cancer, Bladder Carcinoma, Lung Cancer, Lung Neoplasms, Oncology. This article was prepared by Clinical Oncology Week editors from staff and other reports. Copyright 2007, Clinical Oncology Week via NewsRx.com.
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