Reports on bladder cancer findings from National Cancer Institute provide new insights
2007 NOV 19 -- According to recent research from the United States, "Fruit and vegetable intake has been linked to bladder cancer risk; however, evidence for other foods or specific dietary factors is inconclusive. The association between diet and bladder cancer risk was evaluated among 912 incident bladder cancer cases and 873 controls in Spain." "Data were consistent with a reduced bladder cancer risk associated with high fruit intake; however, the association was significant only among current smokers (OR (95% Cl) for 5th versus 1st quintile: 0.5 (0.3-0.9), p trend = 0.009). Evaluation of food subgroups showed significant inverse associations with high intakes of berries, Liliaceae vegetables and yellow-orange vegetables. The latter association was stronger among individuals with the GSTM1 present than the null genotype (0.4 (0.2, 0.7) and 0.9 (0.6, 1.3), respectively; p for interaction = 0.04). Meat or fish intake, their cooking methods or level of doneness, or heterocyclic amine intakes were not significantly associated with risk. Intake of folate, other B-vitamins (B12, B6, B2) and retinol was also associated with a reduced risk, the strongest associations being for vitamin B6 (0.6 (0.4, 0.8) p trend = 0.0006) and retinol (0.6 (0.4-0.9) p trend = 0.004)," wrote R. Garciaclosas and colleagues, National Cancer Institute. The researchers concluded: "Our findings indicate that fruit and vegetable intake, as well as B-vitamin and retinol intake might be associated with a reduced bladder cancer risk." Garciaclosas and colleagues published their study in European Journal of Cancer (Food, nutrient and heterocyclic amine intake and the risk of bladder cancer. European Journal of Cancer, 2007;43(11):1731-1740). For additional information, contact R. Garciaclosas, National Cancer Institute, Hormonal & Reproductive Epidemiology Branch, Division Cancer Epidemiology & Genetics, Execut Plaza S, 6120 Execut Blvd., Rockville, MD 20892, USA. Publisher contact information for the European Journal of Cancer is: Elsevier Science Ltd., the Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. Keywords: United States, Rockville, Bladder Cancer, Bladder Carcinoma, Oncology, National Cancer Institute. This article was prepared by Clinical Oncology Week editors from staff and other reports. Copyright 2007, Clinical Oncology Week via NewsRx.com.
|
