Studies from F. Erdemir and colleagues reveal new findings on bladder cancer
2007 NOV 12 -- "Introduction The effects of squamous and/or glandular differentiation in urothelial carcinoma of bladder on recurrence, progression and survival rate were evaluated in this study. Patients and methods Between 1998 and 2003, a total of 223 patients who had been treated with transurethral resection for bladder cancers were evaluated," scientists writing in the journal International Urology and Nephrology report. "The patients were divided into two groups as; Group I: tumor patients with squamous and/or glandular differentiation, Group II: patients without these findings. Results Histologically 189 (84.7%) were conventional urothelial carcinoma and 34 (15.2%) were tumors with squamous and/or glandular differentiation. The mean age of the patients was 64.4 +/- 12.7 (range 36-81) years. Survival rates within a period of 46.23 +/- 14.8 (12-67) months were 76.47% for Group I and 89.94% for Group II (P = 0.027). The stage distribution as pTa, pT1, and >= pT2 was 2 (5.9%), 18 (52.9%), and 14 (41.2%) in Group I and 101 (53.4%), 51 (27%) and 37 (19.6%) in group II, respectively (P = 0.001). There was a statistically significant tendency towards higher stage at presentation in Group I and the grade distribution was significantly higher in Group I than Group II (P < 0.001). Conclusion High recurrence rates and poor prognosis of these patients should be kept in mind in the follow-up period," wrote F. Erdemir and colleagues. The researchers concluded: "In this respect, these patients should be followed up closely." Erdemir and colleagues published their study in International Urology and Nephrology (The effect of squamous and/or glandular differentiation on recurrence, progression and survival in urothelial carcinoma of bladder. International Urology and Nephrology, 2007;39(3):803-807). Additional information can be obtained by contacting F. Erdemir, Yesil1rmak M Bosna C-3 Sok, 7 Mollaogullari Apt K-, TR-60100 Merkez, Tokat, Turkey. The publisher of the journal International Urology and Nephrology can be contacted at: Springer, Van Godewijckstraat 30, 3311 Gz Dordrecht, Netherlands. Keywords: Turkey, Tokat, Bladder Cancer, Bladder Carcinoma, Oncology. This article was prepared by Clinical Oncology Week editors from staff and other reports. Copyright 2007, Clinical Oncology Week via NewsRx.com.
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