Research reports on angiogenesis from University libre of Bruxelles, Cancer Center provide new insights
2007 NOV 12 -- Investigators publish new data in the report 'Progress in magnetic resonance imaging of brain tumours.' According to recent research from Belgium, "Advances in magnetic resonance based techniques have yielded improvements in both high-resolution anatomical imaging and methods to evaluate physiology and function. This review focuses on recent developments in these techniques as applied to pretreatment staging and post-treatment evaluation of brain tumours High-resolution spectroscopic imaging may contribute to pre-therapeutic grading and characterization of gliomas, as can diffusion techniques." "The latter also hold promise in predicting survival in malignant supratentorial astrocytoma and could help to define areas for biopsy. Both methods can differentiate recurrent tumor from radiation injury. Perfusion-weighted magnetic resonance techniques offer potential markers of tumor angiogenesis and capillary permeability, and correlate well with vascular endothelial growth factor expression in grade II and grade III tumours. Functional magnetic resonance imaging can assess whether surgical treatment is feasible and select patients for intraoperative cortical stimulation. Combining multiple parameters in a magnetic resonance based diagnostic strategy could improve overall performance Magnetic resonance imaging provides insights into the physiology of human tumours in a way that is both noninvasive and radiation free," wrote M. Lemort and colleagues, University libre of Bruxelles, Cancer Center. The researchers concluded: "We may expect from these new imaging methods greater specificity in diagnosis and useful tools with which to predict and assess response to therapy." Lemort and colleagues published their study in Current Opinion In Oncology (Progress in magnetic resonance imaging of brain tumours. Current Opinion In Oncology, 2007;19(6):616-22). For additional information, contact M. Lemort, Cancer Centre of the Universite Libre de Bruxelles, Dept. of Medical Imaging, Cancer Centre of the Universite Libre de Bruxelles, Belgium. Publisher contact information for the journal Current Opinion In Oncology is: Lippincott Williams & Wilkins, 530 Walnut St., Philadelphia, PA 19106-3621, USA. Keywords: Belgium, Angiogenesis, Astrocytoma, Brain Cancer, Brain Carcinoma, Oncology, Perfusion, Radiation Injuries, Therapy, Treatment, Tumor Vascularization, VEGF, Vascular Endothelial Growth Factor. This article was prepared by Pain & Central Nervous System Week editors from staff and other reports. Copyright 2007, Pain & Central Nervous System Week via NewsRx.com.
|
