Brugada Syndrome


New data from S. Rituparna et al illuminate research in acute ischemia



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This article was published in Cardiovascular Week, which you can subscribe to online.

2007 SEP 10 -- "The ''J wave'' (also referred to as ''the Osborn wave,'' ''the J deflection,'' or ''the camel's hump'') is a distinctive deflection occurring at the QRS-ST junction. In 1953, Dr. John Osborn described the ''J wave'' as an ''injury current'' resulting in ventricular fibrillation during experimental hypothermia," scientists in Pune, India report.

"Although ''J Wave''' is supposed to be pathognomonic of hypothermia, it is seen in a host of other conditions such as hypercalcemia, brain injury, subarachnoid hemorrhage, cardiopulmonary arrest from over sedation, the Brugada syndrome, vasospastic angina, and idiopathic ventricular fibrillation. However, there is paucity of literature data as regards to ischemic etiology of ''J Wave.'' In this article, we present a case where ''J waves'' were probably induced by ischemia," wrote S. Rituparna and colleagues.

The researchers concluded: "We also discuss the mechanism of ischemia-induced ''J wave'' accentuation and its prognostic implications."

Rituparna and colleagues published their study in Pace - Pacing and Clinical Electrophysiology (Occurrence of ''J waves'' in 12-lead ECG as a marker of acute ischemia and their cellular basis. Pace - Pacing and Clinical Electrophysiology, 2007;30(6):817-819).

For additional information, contact S. Rituparna, Muktashree New Hill View Top Society, Near Vidya Niketan High School, Pune 411037, Maharashtra, India.

The publisher's contact information for the journal Pace - Pacing and Clinical Electrophysiology is: Blackwell Publishing, 9600 Garsington Rd., Oxford OX4 2DQ, Oxon, England.

Keywords: India, Pune, Acute Ischemia, Cardiology, Electrophysiology, Hypothermia, Ventricular Fibrillation.

This article was prepared by Cardiovascular Week editors from staff and other reports. Copyright 2007, Cardiovascular Week via NewsRx.com.