Cancer Therapy
Return to Library
|
Free Cancer Therapy Articles |
- Studies from University Hospital, Department of Oncology in the area of esophageal cancer therapy described
- Studies from University of California have provided new information about breast cancer therapy
- Studies from University of Michigan, Department of Pharmaceutical Sciences in the area of cancer therapy described
- Studies from University of Nijmegen, Department of Urology have provided new data on prostate cancer therapy
- Studies from University of Wisconsin, Department of Surgery yield new information about cancer therapy
- Studies in the area of cancer therapy reported from University College, Cork Cancer Research Center
- Studies in the area of lung cancer therapy reported from European Institute of Oncology, Division of Thoracic Surgery
- Studies in the area of solid cancer therapy reported from College of Medicine
- Study data from A. Svanberg and co-authors update knowledge of cancer therapy
- Study data from Ocean University of China, Marine Drug and Food Institute provide new insights into HIV/AIDS cancer therapy
- Study data from University of Arkansas provide new insights into colon cancer therapy
- Study data from University of Illinois, College of Pharmacy update knowledge of cancer therapy
- Study findings on cancer therapy are outlined in reports from New Cross Hospital, Department of Oncology
- Study results from Capital Medical University in the area of hepatocellular cancer therapy published
- Study results from Memorial Sloan Kettering Cancer Center broaden understanding of cancer therapy
- Study results from Nara Medical University, Department of Urology provide new insights into bladder cancer therapy
- United BioSource Corporation describes research in myelodysplastic syndrome
- University of Ioannina, Department of Chemistry publishes research in cancer therapy
- Data on apoptosis discussed by researchers at University of Bologna
|
|
|
Studies from Safdarjung Hospital have provided new data on cancer therapy
2007 NOV 19 -- New investigation results, 'Relation of cell viability and apoptosis with clinical remission following induction chemotherapy in ALL and AML,' are detailed in a study published in Journal of Experimental & Clinical Cancer Research. "Evaluation of in vitro spontaneous apoptosis of acute leukemic blast cells after incubating for different time period and its correlation with clinical outcome is well documented in the literature. However, there is insufficient information available on the flowcytometric determination of cell viability immediately after separating blast cells and its correlation with the clinical response," scientists in New Delhi, India report. "In this study, we attempted to evaluate the relationship between viability of freshly isolated leukemic cells and the clinical response. Cell viability was evaluated in freshly isolated leukemic cells from 84 patients with acute leukemia (AL) using 7-Amino-Actinomycin D and was correlated with the clinical response following induction chemotherapy. Patients with ALL who achieved complete remission (CR) had significantly lower mean live cell (70.9%) compared to those patients who did not achieve CR (93.3%) (p=0.02). Furthermore, ALL responders had also significantly higher mean early apoptotic cell (19.4%) as compared to non responders (5%) (p=0.04). No significant difference was found in the mean live / early apoptotic cell count of responders and non responders of AML patients. The probability of obtaining CR in ALL patients was 3.7 and 2.7 times higher in those who had mean live cell count less than 70% and apoptotic cell count more than 10%, respectively," wrote B. Bhushan and colleagues, Safdarjung Hospital. The researchers concluded: "A lower cell viability and higher apoptosis in freshly isolated leukemic cells at the time of diagnosis may indicate a favorable response in patients with ALL but may not provide any sufficient information in predicting the response in AML patients to induction chemotherapy." Bhushan and colleagues published their study in the Journal of Experimental & Clinical Cancer Research (Relation of cell viability and apoptosis with clinical remission following induction chemotherapy in ALL and AML. Journal of Experimental & Clinical Cancer Research, 2007;26(3):313-21). For additional information, contact B. Bhushan, Safdarjung Hospital Campus, Institute of Pathology (Indian Council of Medical Research), New Delhi, India. The publisher's contact information for the Journal of Experimental & Clinical Cancer Research is: Apsit Association PROM Stud Immunology Tumor, Viale Regina Elena 291, 00161 Rome, Italy. Keywords: India, New Delhi, Cancer Therapy, Apoptosis, Cancer, Cancer Research, Chemotherapy, Drug Therapy, Oncology, Treatment. This article was prepared by Biotech Business Week editors from staff and other reports. Copyright 2007, Biotech Business Week via NewsRx.com.
|
