Study data from University of California, Division of General Surgery update knowledge of lymphoma therapy
2007 NOV 19 -- Fresh data on lymphoma are presented in the report 'Duodenal lymphoma: a rare and morbid tumor.' "We conducted a retrospective tumor registry review of a 36-year experience in a university center and identified 10 patients with duodenal lymphoma (five localized, five disseminated). Histologic types included diffuse large B-cell in four patients, mucosa-associated lymphoid tumor in three, and Hodgkin, follicular, and unclassified (one each)," scientists in the United States report. "Treatments included chemotherapy in four patients, radiation therapy (RT) in two patients, Helicobacter pylori treatment in two, and observation in one. Five patients underwent operations (emergent in two, elective in three) for indications including massive bleeding in two patients, obstruction in two, or both in one. Survival for surgical group was 25 per cent at 1 year. One-year survival for nonsurgical group was 100 per cent, and all nonoperated patients lived at least 5 years, except for one who is alive 2 years after diagnosis. Surgical patients were younger and had more advanced lesions and less favorable cell types. When operation is required for bleeding or obstruction from secondary tumors in younger patients with disseminated disease, surgical challenges are formidable and survival is very limited," wrote P.J. Chestovich and colleagues, University of California, Division of General Surgery. The researchers concluded: "Tumors of less aggressive histology have far better prognosis." Chestovich and colleagues published their study in The American Surgeon (Duodenal lymphoma: a rare and morbid tumor. The American Surgeon, 2007;73(10):1057-62). For additional information, contact P.J. Chestovich, David Geffen School of Medicine at UCLA, Dept. of Surgery, Division of General Surgery, Los Angeles, California USA.. The publisher's contact information for the journal The American Surgeon is: Southeastern Surgical Congress, 141 West Wieuca Rd., Ste. B100, Atlanta, GA 30342, USA. Keywords: United States, Los Angeles, Lymphoma Therapy, Gastroenterology, Hematology, Lymphoma, Oncology, Therapy, Treatment. This article was prepared by Biotech Business Week editors from staff and other reports. Copyright 2007, Biotech Business Week via NewsRx.com.
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