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Study findings on myeloma are outlined in reports from University of Leeds



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This article was published in Hematology Week, which you can subscribe to online.
2007 NOV 19 -- Researchers in Leeds, the United Kingdom conducted a study "To test the reliability, validity and sensitivity of the European Organisation for Research and Treatment of Cancer (EORTC) QLQ-MY24 questionnaire, designed to assess the quality of life of myeloma patients with the QLQ-C30 The study was carried out through the EORTC Quality of Life Group using clinical trials in seven countries. All trials used the QLQ-C30 and QLQ-MY24 at baseline and a follow-up timepoint Two hundred and forty patients participated."

"The questionnaires were acceptable to patients. The hypothesised scale structure (disease symptoms, side-effects, body image and future perspective) was confirmed by multi-trait scaling, internal consistency and correlation analysis. Most scales demonstrated sensitivity to change and discriminated between clinically different patients," wrote K. Cocks and colleagues, University of Leeds.

The researchers concluded: "The social support scale (4 items) was removed due to observed ceiling effects The final questionnaire contains 20 items, QLQ-MY20, and is a reliable and valid instrument recommended for use with the QLQ-C30 in myeloma patients."

Cocks and colleagues published the results of their research in European Journal of Cancer (An internadional field study of the reliability and validity of a disease-specfic questionnanire module (The QLQ-MY20) in assessing the quality of life of patients with multiple myeloma. European Journal of Cancer, 2007;43(11):1670-1678).

For additional information, contact K. Cocks, University of Leeds, Clinic Trials Research Unit, 17 Springfield Mt, Leeds LS2 9NG, W Yorkshire, UK.

The publisher of the European Journal of Cancer can be contacted at: Elsevier Science Ltd., the Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England.

Keywords: United Kingdom, Leeds, Myeloma, University of Leeds.

This article was prepared by Hematology Week editors from staff and other reports. Copyright 2007, Hematology Week via NewsRx.com.