New congenital hypothyroidism in children data have been reported by H. Sato and co-authors
2007 AUG 28 -- A new study, "Growth of patients with congenital hypothyroidism detected by neonatal screening in Japan," is now available. "The growth of patients with congenital hypothyroidism detected by neonatal screening in Japan was investigated. The data investigated were obtained from Medical Aid Program for Chronic Pediatric Diseases of Specified Categories registered in 2002. The present study included 2341 patients (1030 male, 1311 female) registered as having congenital hypothyroidism," scientists in Japan report. "To investigate the growth of these patients, their heights plotted on cross-sectional growth charts for boys and girls, their bodyweights expressed as percentage of bodyweight for height and the frequency distribution of percentage of bodyweight for height were assessed. Cross-sectional growth charts of both male and female patients showed that the heights of the majority of the patients with congenital hypothyroidism were within ±2SD. Approximately half of the patients with heights below -2SD, had some complications. The mean percentages of ideal bodyweights for height were 103.0 ±12.9% for both sexes (±SD, n=2033), 103.3 ±12.7% for boys, and 102.7 ±12.9% for girls. The frequency distribution of percentage of bodyweight showed no tendency of shifting to either ends in comparison with normal distribution curve. Patients with congenital hypothyroidism detected by neonatal screening had normal growth in general, suggesting that the neonatal screening system is being performed efficiently from detection to treatment of the disease in Japan. However, it remains unclear whether some uncomplicated patients with a height below -2 SD are sufficiently treated or not," wrote H. Sato and colleagues, . The researchers concluded: "Close observation of these patients may be needed." Sato and colleagues published their study in Pediatrics International (Growth of patients with congenital hypothyroidism detected by neonatal screening in Japan. Pediatrics International, 2007;49(4):443-6). For more information, contact H. Sato, Sunrise Children's Clinic, Funabashi Chiba, Japan. Publisher contact information for the journal Pediatrics International is: Blackwell Publishing Asia, 54 University St., PO Box 378, Carlton, Victoria 3053, Australia. Keywords: Japan, Congenital Hypothyroidism, Endocrinology, Epidemiology, Pediatric. This article was prepared by Life Science Weekly editors from staff and other reports. Copyright 2007, Life Science Weekly via NewsRx.com.
|
