Researchers from University of Queensland describe findings in pediatric gastroenterology
2007 NOV 21 -- "There is controversy in the literature regarding the effect of inflammatory bowel disease (IBD) on resting energy expenditure (REE). In many cases this may have resulted from inappropriate adjustment of REE measurements to account for differences in body composition," scientists in Australia report. "This article considers how to appropriately adjust measurements of REE for differences in body composition between individuals with IBD Body composition, assessed via total body potassium to yield a measure of body cell mass (BCM), and REE measurements were performed in 41 children with Crohn disease and ulcerative colitis in the Royal Children's Hospital, Brisbane, Australia. Log-log regression was used to determine the power function to which BCM should be raised to appropriately adjust REE to account for differences in body composition between children The appropriate value to ''adjust'' BCM was found to be 0.49, with a standard error of 0.10 Clearly, there is a need to adjust for differences in body composition, or at the very least body weight, in metabolic studies in children with IBD. We suggest that raising BCM to the power of 0.5 is both a numerically convenient and a statistically valid way of achieving this aim. Under circumstances in which the measurement of BCM is not available, raising body weight to the power of 0.5 remains appropriate," wrote R.J. Hill and colleagues, University of Queensland. The researchers concluded: "The important issue of whether REE is changed in cases of IBD can then be appropriately addressed." Hill and colleagues published their study in the Journal of Pediatric Gastroenterology and Nutrition (Resting energy expenditure in children with inflammatory bowel disease. Journal of Pediatric Gastroenterology and Nutrition, 2007;45(3):342-346). For more information, contact R.J. Hill, University of Queensland, Royal Children's Hospital, Children's Nutrition Research Center, Discipline Pediatric & Child Health, Herston, Qld 4029, Australia. Publisher contact information for the Journal of Pediatric Gastroenterology and Nutrition is: Lippincott Williams & Wilkins, 530 Walnut St., Philadelphia, PA 19106-3621, USA. Keywords: Australia, Pediatric Gastroenterology, University of Queensland. This article was prepared by Fitness & Wellness Business Week editors from staff and other reports. Copyright 2007, Fitness & Wellness Business Week via NewsRx.com.
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