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New subtotal thyroidectomy research from Istanbul University, Medical Department described
2009 JUN 8 - (NewsRx.com) -- "This study aimed to compare the impact of total versus subtotal thyroidectomy on calcium metabolism and bone mineral density in euthyroid, premenopausal women. The study included 24 premenopausal women who had undergone total (n = 10) or subtotal (n = 14) thyroidectomy and who were receiving nonsuppressive doses of thyroxine," scientists writing in the Journal of Laryngology and Otology report. "The median post-operative period was four years. We determined, in all patients, the following parameters associated with calcium metabolism: total serum calcium, inorganic phosphate, intact parathormone, calcitonin and alkaline phosphatase. The bone mineral density of the spine and hip were measured using a Hologic QDR 4500C bone densitometer and were compared with controls matched for age and peak bone mineral density (using the t-test). The measured calcium metabolism parameters were normal in all patients, and none had osteoporosis. There was no significant difference in the bone mineral density measurements for the spine and hip, comparing patients who had undergone total versus subtotal thyroidectomy (using the t-test)," wrote F. Tunca and colleagues, Istanbul University, Medical Department. The researchers concluded: "The impact of total thyroidectomy on bone mineral metabolism is not significantly different front that of subtotal thyroidectomy, in premenopausal women with normal thyroid-stimulating hormone values." Tunca and colleagues published their study in the Journal of Laryngology and Otology (Impact of total versus subtotal thyroidectomy on calcium metabolism and bone mineral density in premenopausal women. Journal of Laryngology and Otology, 2009;123(4):434-438). Additional information can be obtained by contacting F. Tunca, Istanbul University, Istanbul Faculty Medical, Dept. of General Surgery, TR-34390 Capa, Topkapi, Turkey. The publisher of the Journal of Laryngology and Otology can be contacted at: Cambridge University Press, Edinburgh Bldg, Shaftesbury Rd., CB2 8RU Cambridge, England. Keywords: Turkey, Capa, Bone, Calcitonin, Drugs, Laryngology, Metabolism, Otology, Phosphatase, Subtotal Thyroidectomy, Surgery, Therapy, Treatment, Istanbul University, Medical Department. This article was prepared by Biotech Business Week editors from staff and other reports. Copyright 2009, Biotech Business Week via NewsRx.com.
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