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Researchers at University of Edinburgh Target Veterinary Research

2013 JAN 1 (NewsRx) -- By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on Veterinary Research. According to news reporting originating from Midlothian, United Kingdom, by NewsRx correspondents, research stated, "Equine periodontal disease (EPD) is a common and painful condition, the aetiology and pathology of which are poorly understood. To characterise the histopathological lesions associated with EPD, the skulls of 22 horses were assessed grossly for the presence of periodontal disease, and a standard set of interdental tissues taken from each for histopathological examination."

Our news editors obtained a quote from the research from the University of Edinburgh, "Histological features of EPD included ulceration and neutrophilic inflammation of the gingival epithelium. Mononuclear and eosinophilic inflammation of the gingival lamina propria and submucosa was commonly present irrespective of the presence or degree of periodontal disease. Gingival hyperplasia was present to some degree in all horses, and was only weakly associated with the degree of periodontal disease. In all horses dental plaque was present at the majority of sites examined and was often associated with histological evidence of peripheral cemental erosion. Bacteria (including spirochaetes in four horses) were identified in gingival samples by Gram and silver impregnation techniques and were significantly associated with the presence of periodontal disease. This is the first study to describe histological features of EPD, and the first to identify associated spirochaetes in some cases. Histological features were variable, and there was considerable overlap of some features between the normal and diseased gingiva."

According to the news editors, the research concluded: "Further investigation into the potential role of bacteria in the pathogenesis and progression of EPD is warranted."

For more information on this research see: Histopathological lesions associated with equine periodontal disease. Veterinary Journal, 2012;194(3):386-91. (Elsevier - www.elsevier.com; Veterinary Journal - www.elsevier.com/wps/product/cws_home/623077)

The news editors report that additional information may be obtained by contacting A. Cox, Veterinary Pathology Unit, University of Edinburgh, Easter Bush Veterinary Centre, Roslin, Midlothian EH25 9RG, UK.

Keywords for this news article include: Europe, Midlothian, United Kingdom, Veterinary Research.

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