Dermatofibrosarcoma Protuberans
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Data on dermatology published by researchers at Korea University, Department of Dermatology
2009 JUN 30 - (NewsRx.com) -- New research, 'Congenital Bednar's tumour,' is the subject of a report. According to recent research from Seoul, Korea, "Bednar's tumor (BT) is a rare variant of dermatofibrosarcoma protuberans (DFSP). In addition to the typical histological findings of DFSP, melanin-containing dendritic cells are found in BT." "Its occurrence at birth is very rare and there have been only two case reports of congenital BT in the English literature. A 12-year-old boy presented with a single, dome-shaped erythematous nodule, 25 x 15 mm in size, on the lower back. The lesion was present as a depressed patch at birth. Subsequently the lesion grew gradually to a dome-shaped mass. Histopathological examination found a dense infiltration of spindle cells arranged in a storiform pattern in the dermis, with pigmented cells admixed with the spindle cells. Cell mitosis and atypia were rarely seen. On immunohistochemical study, the tumor cells were positive for CD34 and melanin-containing cells were positive for S-100. A diagnosis of BT was made and the mass was removed by wide local excision," wrote J.W. Kim and colleagues, Korea University, Department of Dermatology. The researchers concluded: "There was no evidence of recurrence at follow-up 8 months later." Kim and colleagues published their study in Clinical & Experimental Dermatology (Congenital Bednar's tumour. Clinical & Experimental Dermatology, 2009;34(5):e85-7). For additional information, contact J.W. Kim, Korea University Medical College, Dept. of Dermatology, Seoul, Korea. Publisher contact information for the journal Clinical & Experimental Dermatology is: Blackwell Publishing Inc., 350 Main St., Malden, MA 02148, USA. Keywords: Korea, Seoul, Dermatofibrosarcoma, Experimental Dermatology. This article was prepared by Life Science Weekly editors from staff and other reports. Copyright 2009, Life Science Weekly via NewsRx.com.
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