Studies from National Taiwan University, Institute of Microbiology and Biochemistry describe new findings in drug resistance
2007 NOV 19 -- A new study, 'Molecular characterization of class 1 integrons and antimicrobial resistance in Aeromonas strains from foodborne outbreak-suspect samples and environmental sources in Taiwan,' is now available. "One hundred thirty-three Aeromonas spp. isolates were examined for multiple antibiotic resistance phenotypes and prevalence of class 1 integron sequences. Twenty-four (18.0%) of these isolates contained class 1 integron," researchers in Taipei, Taiwan report. "Seven different class 1 integrons were found among 24strains, with a total of 10 different gene cassettes encoding for resistance to trimethoprim (dfr12 and dfr2d), aminoglycosides (aadA1 and aadA2), beta-lactam antibiotics (oxa2), chloramphenicol (catB3 and catB8), quaternary ammonium amines (qacE2), and 2 ORFs (orfD and orfF) with unknown function. Rate of antibiotic resistance was different between integron-positive and integron-negative strains. Trimethoprim and trimethoprim-sulphamethoxazole resistances were commonly associated with integron, and all of integron-positive isolates were multiple resistant to more than 3 agents. Resistance to as many as 10 antimicrobial agents were observed in integron-positive strains. Several cassette arrays of class 1 integrons identified in this study were not previously reported in Aeromonas strains," wrote Y.C. Chang and colleagues, National Taiwan University, Institute of Microbiology and Biochemistry. The researchers concluded: "This study demonstrates the wide distribution of class 1 integron in Aeromonas spp. isolated from foodborne outbreak-suspect samples and environmental sources in Taiwan." Chang and colleagues published their study in Diagnostic Microbiology and Infectious Disease (Molecular characterization of class 1 integrons and antimicrobial resistance in Aeromonas strains from foodborne outbreak-suspect samples and environmental sources in Taiwan. Diagnostic Microbiology and Infectious Disease, 2007;59(2):191-7). For additional information, contact Y.C. Chang, Institute of Microbiology and Biochemistry, National Taiwan University, Taipei 106, Taiwan. Publisher contact information for the journal Diagnostic Microbiology and Infectious Disease is: Elsevier Science Inc., 360 Park Avenue South, New York, NY 10010-1710, USA. Keywords: Taiwan, Taipei, Anti-Infectives, Antibiotics, Antimicrobial Resistance, Antimicrobials, Diagnostics, Drug Resistance, Therapy, Treatment. This article was prepared by Anti-Infectives Week editors from staff and other reports. Copyright 2007, Anti-Infectives Week via NewsRx.com.
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