Embryogenesis
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Reports summarize enzyme research from University of Freiburg, Institute of Anatomy and Cell Biology
2009 AUG 24 - (NewsRx.com) -- Researchers detail in 'Cystathionine gamma-lyase expression during avian embryogenesis,' new data in enzyme research. According to a study from Freiburg, Germany, "Cystathionine gamma-lyase (CSE) is a key enzyme in the trans-sulphuration pathway for the biosynthesis of cysteine from methionine and catalyses the hydrolysis of cystathionine into cysteine. It has been reported to be expressed in mammalian liver and kidney but so far no comprehensive developmental expression analysis of CSE has been available." "We cloned a 600 bp fragment of chick CSE cDNA and analysed its expression pattern during avian embryonic development until embryonic day 13. We found CSE expression in various developing organs including the notochord, eye, neural tube, limb bud mesenchyme and sclerotomal compartment of the somites. Notably, prominent expression was found in renal epithelia throughout kidney development, i.e. in the tubular structures of pronephros, mesonephros and metanephros," wrote S. Kruck and colleagues, University of Freiburg, Institute of Anatomy and Cell Biology. The researchers concluded: "Our data introduce CSE as a novel marker gene to study avian kidney development." Kruck and colleagues published their study in the Journal of Anatomy (Cystathionine gamma-lyase expression during avian embryogenesis. Journal of Anatomy, 2009;215(2):170-5). For more information, contact S. Kruck, University of Freiburg, Dept. of Molecular Embryology, Institute of Anatomy and Cell Biology, Freiburg, Germany. Publisher contact information for the Journal of Anatomy is: Blackwell Publishing Inc., 350 Main St., Malden, MA 02148, USA. Keywords: Germany, Freiburg, Anatomy, Cysteine, Dietary Supplement, Enzyme Research, Lyase, Nutritional Supplement. This article was prepared by Biotech Business Week editors from staff and other reports. Copyright 2009, Biotech Business Week via NewsRx.com.
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