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Researchers from Oita University describe findings in life sciences
2009 AUG 4 - (NewsRx.com) -- Research findings, 'Effect of nanoparticles on the male reproductive system of mice,' are discussed in a new report. "The effects of nanoparticles toward on the male reproductive system of mice were investigated. Three sizes (14, 56 and 95 nm) of carbon black nanoparticles were intratracheally administered (0.1 mg/mouse for 10 times every week) to ICR male mice to investigate their adverse effects on the reproductive function," scientists in Oita, Japan report. "The serum testosterone levels were elevated significantly in the 14-and 56-nm carbon nanoparticles-exposed groups. Histological examination showed partial vacuolation of the seminiferous tubules. In addition, the effects of particle number towards the male reproductive system were investigated. The particle number controlled 14-nm nanoparticles-exposed group (14 N group, which has approximately the same particle number per unit volume as the 56-nm nanoparticles) showed fewer effects than did the 56-nm nanoparticles-exposed groups. These results suggest that carbon nanoparticle-exposure has adverse effects on the mouse male reproductive function," wrote S. Yoshida and colleagues, Oita University. The researchers concluded: "Furthermore, the effects of nanoparticles on the male reproductive system depend on particle mass rather than particle number." Yoshida and colleagues published their study in International Journal of Andrology (Effect of nanoparticles on the male reproductive system of mice. International Journal of Andrology, 2009;32(4):337-42). For more information, contact S. Yoshida, Oita University of Nursing and Health Sciences, Dept. of Health and Sciences, Oita, Japan. Publisher contact information for the International Journal of Andrology is: Blackwell Publishing Inc., 350 Main St., Malden, MA 02148, USA. Keywords: Japan, Oita, Life Sciences, Testosterone, Pharmaceuticals, Drugs, Therapy, Treatment, Epidemiology, Andrology. This article was prepared by Drug Law Weekly editors from staff and other reports. Copyright 2009, Drug Law Weekly via NewsRx.com.
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