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Tor Vergata University Details Research in Obesity

2012 NOV 2 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Current study results on Obesity have been published. According to news reporting originating from Rome, Italy, by NewsRx correspondents, research stated, "Intrauterine growth retardation predisposes toward long-term morbidity from type 2 diabetes and cardiovascular disease. To explain this association, the concept of programming was introduced to indicate a process whereby a stimulus or insult at a critical period of development has lasting or lifelong consequences on key endocrine and metabolic pathways."

Our news editors obtained a quote from the research from Tor Vergata University, "Subtle changes in cell composition of tissues, induced by suboptimal conditions in utero, can influence postnatal physiological functions. There is increasing evidence, suggesting that liver may represent one of the candidate organs targeted by programming, undergoing structural, functional and epigenetic changes following exposure to an unfavorable intrauterine environment."

According to the news editors, the research concluded: "The aim of this review is to provide insights into the molecular mechanisms underlying liver programming that contribute to increase the cardiometabolic risk in subjects with intrauterine growth restriction."

For more information on this research see: Effect of intrauterine growth retardation on liver and long-term metabolic risk. International Journal of Obesity, 2012;36(10):1270-7. (Nature Publishing Group - www.nature.com/; International Journal of Obesity - www.nature.com/ijo/)

The news editors report that additional information may be obtained by contacting S. Cianfarani, Molecular Endocrinology Unit-DPUO, Bambino Gesu Children's Hospital - 'Rina Balducci' Center of Pediatric Endocrinology, Tor Vergata University, Rome, Italy.

Keywords for this news article include: Rome, Italy, Europe, Obesity, Fetal Growth Retardation.

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