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New findings from Charles University, Department of Internal Medicine in the area of microcirculation published
2009 JUN 1 - (NewsRx.com) -- Fresh data on microcirculation are presented in the report 'The importance of rheological parameters in the therapy of microcirculatory disorders.' "Rheological conditions basically influence tissue perfusion, oxygen and nutrient supply, tissue regeneration and in its consequence the course of pathological processes, especially in microcirculation and partially even in macrocirculation. Haemorheotherapy has shown to be successful in several indications (critical disorders in microcirculation) when other methods of therapy have failed," investigators in Czech Republic report. "In this study we describe the changes of effectivity indicators in haemorheopheresis treatment and their clinical importance in cases of eye microcirculation, statoacoustic apparatus and disorders of the lower extremities. We treated with haemorheopheresis (separator Cobe.Spetra + Evaflux filter) 24 patients (16 patients with age related macular degeneration, 5 with critical peripheral arterial foot disease, and 3 with acute hearing loss). After the procedures alpha2-macroglobulin decreases by about 58%, fibrinogen by about 69%, IgM by about 61%, LDL-cholesterol by about 77%, apolipoprotein B by about 76% and lipoprotein(a) by about 63%. It corresponds with a decrease in blood and plasma viscosity and clinical improvement in the observed patients, i.e. visual improvement, acceleration of tissue defect healing and improvement in hearing. We noticed 7.1% clinically insignificant side-effects. The method of haemorheopheresis was safe," wrote M. Bláha and colleagues, Charles University, Department of Internal Medicine. The researchers concluded: "It led to improvement in patients' clinical condition in the above mentioned indications when other methods of treatment failed." Bláha and colleagues published their study in Clinical Hemorheology and Microcirculation (The importance of rheological parameters in the therapy of microcirculatory disorders. Clinical Hemorheology and Microcirculation, 2009;42(1):37-46). For additional information, contact M. Bláha, Haematology, IInd Dept. of Internal Medicine, Medical Faculty, Charles University, Hradec Kralove, Czech Republic. The publisher of the journal Clinical Hemorheology and Microcirculation can be contacted at: IOS Press, Nieuwe Hemweg 6B, 1013 BG Amsterdam, The Netherlands. Keywords: Czech Republic, Angiology, Hemorheology, Internal Medicine, Microcirculation, Perfusion, Therapy, Tissue Regeneration, Treatment. This article was prepared by Biotech Business Week editors from staff and other reports. Copyright 2009, Biotech Business Week via NewsRx.com.
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