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Research conducted at Yokohama City University has provided new information about squamous cell carcinoma
2009 JUL 20 - (NewsRx.com) -- According to recent research from Yokohama, Japan, "We aimed to estimate whether the macroscopic extent of gastric mucosal atrophy is associated with a risk for esophageal squamous cell carcinoma using a case-control study in Japanese subjects, a population known to have a high prevalence of CagA-positive H. pylori infection. Two hundred and fifty-three patients who were diagnosed as having esophageal squamous cell carcinoma, and 253 sex-and age-matched controls were enrolled in the present study." "The macroscopic extent of gastric mucosal atrophy was evaluated based on the Kimura and Takemoto Classification. A conditional logistic regression model with adjustment for potential confounding factors was used to assess the associations. Body gastritis, defined endoscopically, was independently associated with an increased risk for esophageal squamous cell carcinoma. Our findings suggest that macroscopic body gastritis may be a risk factor for esophageal squamous cell carcinoma in Japan," wrote T. Akiyama and colleagues, Yokohama City University. The researchers concluded: "Further studies are needed to confirm these findings." Akiyama and colleagues published their study in BMC Gastroenterology (Macroscopic extent of gastric mucosal atrophy: increased risk factor for esophageal squamous cell carcinoma in Japan. BMC Gastroenterology, 2009;9():34). For additional information, contact M. Inamori, Yokohama City University, School Medical, Division Gastroenterology, Kanazawa Ku, 3-9 Fukuura, Yokohama, Kanagawa 232, Japan. Publisher contact information for the journal BMC Gastroenterology is: Biomedical Central Ltd., Current Science Group, Middlesex House, 34-42 Cleveland St., London W1T 4LB, England. Keywords: Japan, Yokohama, Atrophy, Clinical Trial Research, Gastroenterology, Infectious Disease, Neurology, Oncology, Squamous Cell Carcinoma, Yokohama City University. This article was prepared by Biotech Business Week editors from staff and other reports. Copyright 2009, Biotech Business Week via NewsRx.com.
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