Giant Cell Arteritis
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Study data from G.S. Breuer et al provide new insights into giant cell arteritis
2009 MAY 25 - (NewsRx.com) -- In this recently published study, investigators in Jerusalem, Israel conducted a study "To determine to what extent performing simultaneous bilateral temporal artery biopsies might increase the diagnostic sensitivity in giant cell arteritis (GCA). In total 173 consecutive pathology reports of temporal artery biopsies were reviewed for histological findings by a single pathologist." "The rate of discordance of biopsy results was calculated in patients with GCA. Biopsies were performed bilaterally and simultaneously in 132 cases;, 51 had positive results. In 38 the biopsy was positive on both sides (concordant results), while in 13 patients only one side was positive (discordant results), reaching a discordance rate of 13/51 = 0.255. Therefore 12.7% of the patients (one-half of the discordance rate) could have been misdiagnosed as biopsy-negative had a biopsy been done only unilaterally in those 51 cases," wrote G.S. Breuer and colleagues. The researchers concluded: "These data suggest that performing bilateral temporal artery biopsies increases the diaanostic sensitivity of the procedure by up to 12.7%, compared to unilateral biopsies. (First Release Feb 15 2009; J Rheumatol 200936:794-6; doi: 10.3899/jrheum.080792)'." Breuer and colleagues published their study in the Journal of Rheumatology (Rate of Discordant Findings in Bilateral Temporal Artery Biopsy to Diagnose Giant Cell Arteritis. Journal of Rheumatology, 2009;36(4):794-796). For additional information, contact G.S. Breuer, Shaare Zedek Med Center, Dept. of Internal Medical, POB 3235, IL-91031 Jerusalem, Israel. The publisher of the Journal of Rheumatology can be contacted at: J Rheumatol Publ Co., 920 Yonge St., Suite 115, Toronto, Ontario M4W 3C7, Canada. Keywords: Israel, Jerusalem, Biopsy, Cardiology, Diagnostics, Giant Cell Arteritis, Pathology, Rheumatology, Surgery, Temporal Arteritis. This article was prepared by Gastroenterology Week editors from staff and other reports. Copyright 2009, Gastroenterology Week via NewsRx.com.
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