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Reports outline lung transplants study findings from Johns Hopkins University, Medical Department
2009 JUN 1 - (NewsRx.com) -- According to recent research from the United States, "A. Balagopal, L. Mills, A. Shah, A. Subramanian. Detection and treatment of Strongyloides hyperinfection syndrome following lung transplantation.Transpl Infect Dis 2009: 11: 149-154." "All rights reserved Strongyloides hyperinfection syndrome has not been reported in lung transplant recipients. We describe the case of a 61-year-old Peruvian man, who received bilateral lung transplants for idiopathic pulmonary fibrosis, and subsequently developed persistent fever with pulmonary infiltrates, ventilator dependence, and pneumothoraces. Bronchoalveolar lavage (BAL) cultures for bacteria, viruses, and fungi were negative, but testing for ova and parasites from BAL fluid revealed Strongyloides stercoralis larvae on day 16 post transplant. He was successfully treated with albendazole and ivermectin, and immunosuppression was reduced. BAL fluid also grew Mycobacterium kansasii, for which he received combination anti-mycobacterial therapy," wrote A. Balagopal and colleagues, Johns Hopkins University, Medical Department. The researchers concluded: "This case illustrates the importance of screening for parasitic infections before transplantation in the appropriate clinical setting, and demonstrates the utility of direct diagnostic evaluation for parasitic infections in at-risk post-transplant patients with unexplained illnesses." Balagopal and colleagues published their study in Transplant Infectious Disease (Detection and treatment of Strongyloides hyperinfection syndrome following lung transplantation. Transplant Infectious Disease, 2009;11(2):149-154). For additional information, contact A. Balagopal, Johns Hopkins University, School Medical, Dept. of Medical, 1830 E Monument St., Room 450D, Baltimore, MD 21287, USA. Publisher contact information for the journal Transplant Infectious Disease is: Wiley-Blackwell Publishing, Inc., Commerce Place, 350 Main St., Malden 02148, MA, USA. Keywords: United States, Baltimore, Lung Transplants, Helminthiasis, Hepatology, Idiopathic Pulmonary Fibrosis, Lung Transplant, Organ Transplant, Pulmonary Fibrosis, Respirology, Strongyloidiasis, Transplantation, Johns Hopkins University, Medical Department. This article was prepared by Hematology Week editors from staff and other reports. Copyright 2009, Hematology Week via NewsRx.com.
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