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Studies from Sanquin Research provide new data on life sciences
2007 OCT 16 -- A new study, 'Resistance of surface-dried virus to common disinfection procedures,' is now available. According to a study from Amsterdam, Netherlands, "It is believed that surface-dried viruses can remain infectious and may therefore pose a threat to public health. To help address this issue, we studied 0.1 N NaOH and 0.1% hypochlorite for their capacity to inactivate surface-dried lipid-enveloped (LE) [human immunodeficiency virus (HIV), bovine viral diarrhoea virus (BVDV) and pseudorabies virus (PRV)] and non-lipid-enveloped [NLE; canine parvovirus (CPV) and hepatitis A virus (HAV)] viruses in a background of either plasma or culture medium." "In addition, 80% ethanol was tested on surface-dried LE viruses. Without treatment, surface-dried LE viruses remained infectious for at least one week and NLE viruses for more than one month. Irrespective of the disinfectant, inactivation decreased for viruses dried in plasma, which is more representative of viral contaminated blood than virus in culture medium. Inactivation by all disinfectants improved when preceded by rehydration, although the infectivity of CPV actually increased after rehydration and disinfection may thus be overestimated in the absence of rehydration. This is the first comprehensive study of five important (model) viruses in a surface-dried state showing persistence of infectivity, resistance to three commonly used disinfectants and restoration of susceptibility after rehydration," wrote F.G. Terpstra and colleagues, Sanquin Research. The researchers concluded: "Our results may have implications for hygiene measurements in the prevention of virus transmission." Terpstra and colleagues published their study in the Journal of Hospital Infection (Resistance of surface-dried virus to common disinfection procedures. Journal of Hospital Infection, 2007;66(4):332-8). For more information, contact F.G. Terpstra, Academic Medical Center of the University of Amsterdam, Sanquin Research, Landsteiner Laboratory, Center for Infection and Immunity Amsterdam, Amsterdam, Netherlands. Publisher contact information for the Journal of Hospital Infection is: W B Saunders Co. Ltd., 32 Jamestown Rd., London NW1 7BY, England. Keywords: Netherlands, Amsterdam, Life Sciences, Virus, Viral. This article was prepared by Disease Prevention Week editors from staff and other reports. Copyright 2007, Disease Prevention Week via NewsRx.com.
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