Ichthyosis
Return to Library
Researchers from St. Vincent's University, Department of Dermatology report on findings in mycosis fungoides
2009 JUN 30 - (NewsRx.com) -- Current study results from the report, 'Juvenile folliculotropic and ichthyosiform mycosis fungoides,' have been published. "Ichthyosiform mycosis fungoides (MF) is a recently recognized clinical variant of MF, which appears as dry scaling patches and plaques, or as a generalized eruption. Acquired ichthyosis is well recognized as a paraneoplastic cutaneous presentation of malignancy, especially in lymphoproliferative disorders," scientists writing in the journal Clinical & Experimental Dermatology report. "In contrast, the ichthyosiform eruption in ichthyotic MF is attributable to infiltration of the skin by tumor cells. We report the case of a 15-year-old boy who presented with a 5-year history of enlarging pruritic plaques on the forehead and back, patchy alopecia and generalized ichthyosis. Histology of the forehead and back showed a dense, lymphocytic, folliculocentric and perivascular infiltrate of predominantly CD4-positive T cells consistent with folliculotropic MF. Histological examination of biopsies from ichthyotic skin found similar features," wrote C. Ryan and colleagues, St. Vincent's University, Department of Dermatology. The researchers concluded: "Our patient had a histological diagnosis at the age of 15 years, making him the youngest reported patient with either folliculotropic MF or ichthyotic MF." Ryan and colleagues published their study in Clinical & Experimental Dermatology (Juvenile folliculotropic and ichthyosiform mycosis fungoides. Clinical & Experimental Dermatology, 2009;34(5):e160-2). Additional information can be obtained by contacting C. Ryan, St. Vincent's University Hospital, Dept. of Dermatology, Elm Park, Dublin, Ireland. The publisher of the journal Clinical & Experimental Dermatology can be contacted at: Blackwell Publishing Inc., 350 Main St., Malden, MA 02148, USA. Keywords: Ireland, Dublin, Dermatology, Experimental Dermatology, Ichthyosis, Lymphoproliferative Disorder, Mycosis Fungoides. This article was prepared by Life Science Weekly editors from staff and other reports. Copyright 2009, Life Science Weekly via NewsRx.com.
|
