Immunotherapy


Research results from D. Saporta and co-authors update knowledge of immunotherapy



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2007 NOV 21 -- According to recent research published in the ENT - Ear Nose & Throat Journal, "We performed an observational study to determine whether allergen-specific sublingual inummotherapy (SLIT) is as effective as allergen-specific subcutaneous injection immunotherapy(SCIT). Our study population was comprised of 66 patients who had been taking SLIT Of this group, 36 patients had switched to SLIT after having been treated with SCIT (group I), while the remaining 30 patients had received SLIT only (group II)."

"A questionnaire was used to evaluate the results of treatment. In group 1, 33 patients (92%) gave SLIT a favorable rating; 27 of these patients (75%) said it was just as effective as SCIT and 6 (17%) said it was actually superior (the remaining 3 patients [8%] said that SCIT was better). In group 11, 2 7 of 30 patients (90%) said they had attained symptom relief with SLIT21 (70%) said that the relief had been very significant. Overall, 60 of the 66 patients (91%) expressed various degrees of satisfaction with SLIT We believe that our SLIT protocol, which is based on established guidelines for SCIT administration, is an effective, safe, well-tolerated, and easy-to-use regimen," wrote D. Saporta and colleagues.

The researchers concluded: "Future prospective studies of larger groups are clearly indicated."

Saporta and colleagues published their study in ENT - Ear Nose & Throat Journal (Efficacy comparison of multiple-antigen subcutaneous injection immunotherapy and multiple-antigen sublingual immunotherapy. ENT - Ear Nose & Throat Journal, 2007;86(8):493-497).

For additional information, contact D. Saporta, 470 N Avenue, Elizabeth, NJ 07208, USA.

The publisher's contact information for the ENT - Ear Nose & Throat Journal is: Vendome Group LLC, 149 Fifth Avenue, 10TH Floor, New York, NY 10010, USA.

Keywords: United States, Biological Therapy, Immunotherapy, Treatment.

This article was prepared by Immunotherapy Weekly editors from staff and other reports. Copyright 2007, Immunotherapy Weekly via NewsRx.com.