Research from Children's Hospital provides new data about mumps vaccines
2007 OCT 29 -- New research, 'Safety of measles, mumps and rubella vaccination in juvenile idiopathic arthritis,' is the subject of a report. According to recent research from Netherlands, "' To assess the effect of measles, mumps and rubella (MMR) vaccination on disease activity in children with juvenile idiopathic arthritis (JIA). A retrospective observational multicentre cohort study was performed in 314 patients with JIA, born between 1989 and 1996." "Disease activity and medication use were compared during the period of 6 months before vaccination versus 6 months after vaccination. Disease activity was measured by joint counts, the Physician's global assessment scale and erythrocyte sedimentation rate. Next, we compared disease activity in patients vaccinated between 8 and 9 years of age with the activity in patients who had not been vaccinated at this time (who received MMR between the ages of 9 and 10 years). No increase in disease activity or medication use was seen in the 6 months after MMR vaccination (n=207), including in patients using methotrexate (n=49). No overt measles infections were noted. When disease activity in vaccinated patients (n=108) was compared with activity in those not yet vaccinated (n=86), there were no significant differences. The MMR booster vaccination does not seem to aggravate disease activity in JIA. This indicates that the most patients with JIA can be vaccinated safely with the MMR vaccine," wrote M.W. Heijstek and colleagues, Children's Hospital. The researchers concluded: "A prospective study is recommended." Heijstek and colleagues published their study in Annals of the Rheumatic Diseases (Safety of measles, mumps and rubella vaccination in juvenile idiopathic arthritis. Annals of the Rheumatic Diseases, 2007;66(10):1384-7). For additional information, contact M.W. Heijstek, Wilhelmina Children's Hospital, Dept. of Paediatric Immunology, University Medical Centre Utrecht, Room KC 03-0630, PO Box 85090, 3508 AB Utrecht, Netherlands. Publisher contact information for the journal Annals of the Rheumatic Diseases is: B M J Publishing Group, British Med Association House, Tavistock Square, London WC1H 9JR, England. Keywords: Netherlands, Mumps Vaccines, Arthritis, Clinical Trial Research, Infectious Disease, Juvenile Rheumatoid Arthritis, Measles, Mumps, Rheumatic Disease, Rubella. This article was prepared by Pain & Central Nervous System Week editors from staff and other reports. Copyright 2007, Pain & Central Nervous System Week via NewsRx.com.
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