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Keratoconus


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Free Keratoconus Articles


Scientists at University of California report research in histopathology



2009 JUL 14 - (NewsRx.com) -- In this recent report published in the journal Cornea, researchers in the United States conducted a study "To describe characteristic histopathologic markers in deep anterior lamellar keratoplasty (DALK) using pneumatic dissection: Anwar ''big-bubble'' technique. Case reports. Deep stromal buttons from 2 patients with keratoconus who had undergone DALK surgery using the ''big-bubble'' technique were examined by light microscopy."

"The histopathology of excised corneal buttons demonstrated multiple intrastromal spaces consistent with air bubbles. Apical stromal thinning seen clinically was not as readily appreciated on histopathology. Pneumatic dissection in DALK produces diffuse intrastromal air bubbles that may mask the corneal thinning that usually characterizes keratoconus histopathologically," wrote P. Lim and colleagues, University of California.

The researchers concluded: "This is a characteristic finding of which ocular pathologists and cortical surgeons should be aware."

Lim and colleagues published their study in Cornea (Histopathology of Deep Anterior Lamellar Keratoplasty With Pneumatic Dissection: The ''Big-Bubble'' Technique. Cornea, 2009;28(5):579-582).

For additional information, contact M.J. Mannis, University of California, Dept. of Ophthalmology & Vis Science, 4860 Y St., Suite 2400, Sacramento, CA 95817, USA.

The publisher's contact information for the journal Cornea is: Lippincott Williams & Wilkins, 530 Walnut St., Philadelphia, PA 19106-3621, USA.

Keywords: United States, Sacramento, Histopathology, Keratoconus, Microscopy, Ophthalmology, Pathology, Surgery, University of California.

This article was prepared by Life Science Weekly editors from staff and other reports. Copyright 2009, Life Science Weekly via NewsRx.com.

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