Studies from Karolinska Institut in the area of liver cancer risk factors described
2007 NOV 12 -- Current study results from the report, 'Overweight, obesity and risk of liver cancer: a meta-analysis of cohort studies,' have been published. According to recent research from Stockholm, Sweden, "Cohort studies of excess body weight and risk of liver cancer were identified for a meta-analysis by searching MEDLINE and EMBASE databases from 1966 to June 2007 and the reference lists of retrieved articles. Results from individual studies were combined using a random-effects model." "We identified 11 cohort studies, of which seven on overweight (with a total of 5037 cases) and 10 on obesity (with 6042 cases) were suitable for meta-analysis. Compared with persons of normal weight, the summary relative risks of liver cancer were 1.17 (95% confidence interval (CI): 1.02-1.34) for those who were overweight and 1.89 (95% CI: 1.51-2.36) for those who were obese," wrote S.C. Larsson and colleagues, Karolinska Institut. The researchers concluded: "This meta-analysis finds that excess body weight is associated with an increased risk of liver cancer." Larsson and colleagues published their study in British Journal of Cancer (Overweight, obesity and risk of liver cancer: a meta-analysis of cohort studies. British Journal of Cancer, 2007;97(7):1005-8). For additional information, contact S.C. Larsson, The National Institute of Environmental Medicine, Division of Nutritional Epidemiology, Karolinska Institutet, PO Box 210, Stockholm SE-17177, Sweden. Publisher contact information for the British Journal of Cancer is: Nature Publishing Group, Macmillan Building, 4 Crinan St., London N1 9XW, England. Keywords: Sweden, Stockholm, Liver Cancer Risk Factors, Bariatrics, Liver Cancer, Liver Carcinoma, Obesity, Oncology. This article was prepared by Clinical Oncology Week editors from staff and other reports. Copyright 2007, Clinical Oncology Week via NewsRx.com.
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