Melanosis
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Research from University Autonoma of San Luis Potosi, Dermatology Department reveals new findings on melanosis
2009 JUN 2 - (NewsRx.com) -- Data detailed in 'Molecular structure and concentration of melanin in the stratum corneum of patients with melasma' have been presented. According to recent research from Mexico, "Melasma is an abnormal acquired hyperpigmentation of the face of unknown origin, it is considered a single disease and very little has been found regarding its pathogenesis. It is usually assumed that melasma is due to excessive melanin production, but excessive retention or abnormal metabolism of this molecule has not yet been considered." "In order to search for an alternate explanation for the excessive pigmentation in melasma the molecular structure and concentration of melanin in the stratum corneum of patients with melasma was analyzed using Raman spectroscopy and optical transmission spectroscopy, respectively. From this study it became apparent that in melasma melanin is concentrated in the deeper layers of the skin but its exteriorization remains the same as for healthy skin," wrote B. Moncada and colleagues, University Autonoma of San Luis Potosi, Dermatology Department. The researchers concluded: "Raman spectroscopy measurements showed degraded molecules of melanin in some subjects, which may help explain the variable success rate of the standard therapy." Moncada and colleagues published their study in Photodermatology, Photoimmunology & Photomedicine (Molecular structure and concentration of melanin in the stratum corneum of patients with melasma. Photodermatology, Photoimmunology & Photomedicine, 2009;25(3):159-60). For additional information, contact B. Moncada, Universidad Autonoma de San Luis Potosi, Dermatology Department, Hospital Central Dr. Ignacio Morones Prieto, SLP, Mexico. Publisher contact information for the journal Photodermatology, Photoimmunology & Photomedicine is: Blackwell Publishing Inc., 350 Main St., Malden, MA 02148, USA. Keywords: Mexico, Biotechnology, Dermatology, Hyperpigmentation, Immunology, Melanosis, Metabolism, Photoimmunology, Photomedicine. This article was prepared by Life Science Weekly editors from staff and other reports. Copyright 2009, Life Science Weekly via NewsRx.com.
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