Meniere Disease
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New findings from University of Antwerp in the area of Meniere disease described
2009 JUN 8 - (NewsRx.com) -- "Tenotomy, of the tensor tympani and stapedius tendons in Meniere's disease. In Meniere's disease (MD), when patients have incapacitating vertigo that is resistant to drug treatment, an intratympanic gentamicin application (ITG) is often proposed," researchers in Edegem, Belgium report. "Recently, some authors suggested that tenotomy, sectioning of the tensor tympani and stapedius tendons, could be a promising treatment. We examined whether tenotomy (ST) has additional benefit, compared to ITG alone, with respect to tinnitus, vertigo, and quality of life. We conducted a retrospective survey of the charts of 24 patients with MD who underwent ITG, or ITG plus ST. Baseline data and follow-up assessments were obtained, using the Meniere's Disease Outcomes Questionnaire (MDOQ), the Dizziness Handicap Inventory (DHI), vertigo frequency per month, tinnitus visual analogue scale, and functional level. Failure was determined by the need for an additional procedure. ITG was performed on 15 patients, and 9 patients underwent ITG plus ST. The procedure was sufficient in 53% of the ITG group and in 22% of the ITG plus ST group. No significant difference was found between the two groups concerning MDOQ scores, DHI, functional level, vertigo frequency, and tinnitus. In the ITG group, we found a significant improvement in number of vertigo attacks and the tinnitus visual analogue scale. In the ITG plus ST group, there was a significant reduction in vertigo attacks, but not in tinnitus," wrote C.F.J. Devalck and colleagues, University of Antwerp. The researchers concluded: "This preliminary study suggests no additional benefit of stapedius and tensor tympani tenotomy in the treatment of Meniere's disease patients." Devalck and colleagues published their study in B - ENT (Tenotomy of the tensor tympani and stapedius tendons in Meniere's disease. B - ENT, 2009;5(1):1-6). For additional information, contact C.F.J. Devalck, University of Antwerp, University of Antwerp Hospital, University of Dept. of Otorhinolaryngology & Head & Neck Surgery, AUREA Antwerp University Research Center Equilibrium & Aerosp, Wilrijkstr 10, B-2650 Edegem, Belgium. Publisher contact information for the journal B - ENT is: Royal Belgian Society Ear, Nose, Throat, Head & Neck Surgery, PO Box 1248, Leuven, 00000, Belgium. Keywords: Belgium, Edegem, Audiology, Drugs, Gentamicin Sulfate, Meniere Disease, Otolaryngology, Pharmaceuticals, Quality of Life, Surgery, Tenotomy, Therapy, Tinnitus, Treatment, Vertigo, University of Antwerp. This article was prepared by Biotech Business Week editors from staff and other reports. Copyright 2009, Biotech Business Week via NewsRx.com.
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