Meningioma
Return to Library
Findings from Methodist Hospital, Department of Pathology advance knowledge in adenocarcinoma
2009 AUG 17 - (NewsRx.com) -- Current study results from the report, 'Tumor-to-tumor metastasis to the central nervous system,' have been published. According to a study from the United States, "Tumor-to-tumor metastasis is a well-recognized phenomenon. Meningioma is the most common intracranial host tumor, with the breast and lung being the most common primary sites." "We report herein two such cases of metastasis from pulmonary adenocarcinoma and malignant melanoma (MM) of vulva, respectively. Case 1: a 69-year-old female smoker who had a history of right upper lobectomy of lung for adenocarcinoma presented with a headache and altered mental status, and was found to have a left temporal contrast-enhancing mass with massive surrounding edema on MRI. The resection specimen revealed foci of metastatic adenocarcinoma within a microcystic meningioma. Case 2: a 75-year-old woman with a history of radical vulvectomy for MM died of widespread systemic metastasis of MM. At autopsy, a 2.5 x 2 x 2 cm firm nodule attached to the falx was incidentally found, with focal black discoloration at the periphery of the mass. Histologic examination showed a fibroblastic meningioma with a focus of metastatic MM. Case 1 is the first case report describing a microcystic variant of meningioma harboring metastatic carcinoma," wrote H. Takei and colleagues, Methodist Hospital, Department of Pathology. The researchers concluded: "Although MM is one of the most common metastatic brain tumors, MM-to-meningioma metastasis is reportedly extremely rare, but can occur." Takei and colleagues published the results of their research in Neuropathology (Tumor-to-tumor metastasis to the central nervous system. Neuropathology, 2009;29(3):303-8). For additional information, contact H. Takei, The Methodist Hospital, Dept. of Pathology, 6565 Fannin Street, Houston, TX 77030 USA.. The publisher of the journal Neuropathology can be contacted at: Blackwell Publishing Inc., 350 Main St., Malden, MA 02148, USA. Keywords: United States, Houston, Adenocarcinoma, Edema, Gynecology, Headache, Lobectomy, Melanoma, Meningioma, Neurology, Neuropathology, Pathology, Surgery, Vulvectomy. This article was prepared by Pain & Central Nervous System Week editors from staff and other reports. Copyright 2009, Pain & Central Nervous System Week via NewsRx.com.
|
