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Recent Myositis Ossificans News and Articles


Study Results from Shiraz University of Medical Sciences Broaden Understanding of Cell Biology

2012 NOV 6 (NewsRx) -- By a News Reporter-Staff News Editor at Life Science Weekly -- Fresh data on Cell Biology are presented in a new report. According to news reporting from Shiraz, Iran, by NewsRx journalists, research stated, "Myositis ossificans (MO) is a rare non-neoplastic heterotopic ossification of soft tissue. Histological examination is the gold standard method for diagnosis, but fine needle aspiration (FNA) cytology may aid in presumptive diagnosis of this lesion."

The news correspondents obtained a quote from the research from the Shiraz University of Medical Sciences, "Nine patients with chief complaint of soft tissue mass with clinically suspected MO were selected. FNA of the mass showed low to hypercellular smears, composed of some amorphous pink to bluish material on Wright-Giemsa stain. The predominant cells were oval to spindle-shaped, resembling fibroblasts. Some cells had a high nucleo-cytoplasmic ratio with hyperchromatic nuclei, an irregular nuclear border and prominent nucleoli. Bland-looking osteoblasts and uni-and binucleated chondrocytes were also noted. FNA diagnosis of 4 patients was suggestive of osteosarcoma and of 2 patients suggestive of chondrosarcoma, 2 patients were diagnosed with a benign process and 1 was deferred due to hypocellularity of the smears. Histological examination of the corresponding surgical specimen confirmed the diagnosis of MO. MO cannot be diagnosed on FNA smears without analyzing the clinical and radiological findings."

According to the news reporters, the research concluded: "Experience shows that otherwise MO is mostly misdiagnosed as a malignant lesion."

For more information on this research see: Confusing cytological findings in myositis ossificans. Acta Cytologica, 2012;56(5):565-70. Acta Cytologica can be contacted at: Sci Printers & Publ Inc, PO Drawer 12425 8342 Olive Blvd, St Louis, MO 63132, USA. (Karger - www.karger.com/; Acta Cytologica - content.karger.com/ProdukteDB/produkte.asp'Aktion=JournalHome&ProduktNr=254338)

Our news journalists report that additional information may be obtained by contacting M. Mokhtari, Dept. of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran.

Publisher contact information for the journal Acta Cytologica is: Sci Printers & Publ Inc, PO Drawer 12425 8342 Olive Blvd, St Louis, MO 63132, USA.

Keywords for this news article include: Iran, Asia, Shiraz, Cell Biology, Myositis Ossificans, Neuromuscular Diseases.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2012, NewsRx LLC

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