Necrotizing Fasciitis
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New necrotizing fasciitis research from University of Minnesota described
2009 JUN 22 - (NewsRx.com) -- According to recent research from the United States, "To review Our management of cervical necrotizing fasciitis (CNF) with the use of adjunctive hyperbaric oxygen therapy (HBO). Case series with chart review." "Evaluation of ten patients with CNF between 2001 to 2006. There were live male and six female patients. Mean age was 43 +/- 11 years. Eight cases resulted front an odontogenic Source. Comorbidities included diabetes mellitus, hypertension, and substance abuse. All patients had computed tomography scans performed, received intravenous antibiotics, and underwent surgical debridement. Eight patients underwent surgery within 24 hours. The average number of debridements was 2.2 +/- 0.8. Hospitalization was twice as long for diabetic patients (15.5 +/- 8.16 days) compared with nondiabetic patients (7.5 +/- 1.6 days. P = 0.029). Nine patients had HBO therapy. Combined data revealed a possible decrease in length of hospitalization with HBO therapy (P < 0.001). No mortality was documented. In addition to early and aggressive medical management and surgical debridement, this study suggests that HBO therapy is a beneficial adjunct by potentially decreasing length of hospitalization," wrote C.E. Flanagan and colleagues, University of Minnesota. The researchers concluded: "Randomized trials are still needed to demonstrate its efficacy." Flanagan and colleagues published their study in Otolaryngology - Head and Neck Surgery (Surgical debridement and adjunctive hyperbaric oxygen in cervical necrotizing fasciitis. Otolaryngology - Head and Neck Surgery, 2009;140(5):730-734). For additional information, contact C.E. Flanagan, University of Minnesota, Dept. of Otolaryngology, School Medical, 420 Delaware St. SE, MMC 396, Minneapolis, MN 55455, USA. Publisher contact information for the journal Otolaryngology - Head and Neck Surgery is: Mosby-Elsevier, 360 Park Avenue South, New York, NY 10010-1710, USA. Keywords: United States, Minneapolis, Antibiotics, Diabetes, Diabetes Mellitus, Endocrinology, Hyperbaric Oxygen, Hypertension, Isaac Syndrome, Laryngology, Necrotizing Fasciitis, Otolaryngology, Surgery, Therapy, Treatment, University of Minnesota. This article was prepared by Anti-Infectives Week editors from staff and other reports. Copyright 2009, Anti-Infectives Week via NewsRx.com.
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