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New carcinoma prognosis study findings recently were published by researchers at Wakayama Medical University, Department of Human Pathology
2009 JUN 22 - (NewsRx.com) -- Research findings, 'Classification of follicular cell tumors of the thyroid gland: analysis involving Japanese patients from one institute,' are discussed in a new report. "Prognostic analyses of thyroid carcinomas of follicular cell origin were carried out on patients treated at Kuma Hospital, Kobe, Japan. A new histopathological classification based on the prognostic evidence is proposed in this study, and it is applicable to the patients treated curatively," scientists writing in the journal Pathology International report. "Major histological types of papillary carcinoma, follicular carcinoma and poorly differentiated carcinoma were combined into one single entity of follicular cell adenocarcinoma because (i) they have the same cell origin (follicular cell); (ii) clear-cut separation of papillary and follicular carcinoma is not always possible, and 10 year cause-specific survival was essentially similar when the patients were treated curatively; and (iii) poorly differentiated carcinoma usually has a background of either papillary or follicular carcinoma. This adenocarcinoma together with undifferentiated carcinoma was stratified into four prognostic groups using pure morphological criteria of the degree of cellular differentiation and histological grade. They are termed well-differentiated adenocarcinoma, moderately differentiated adenocarcinoma, poorly differentiated carcinoma and undifferentiated carcinoma of the thyroid. The 10 year disease-free survival rates were 86.3-93.1%, 65.4-78.7%, and 43.0-53.8%, and 0%, respectively," wrote K. Kakudo and colleagues, Wakayama Medical University, Department of Human Pathology. The researchers concluded: "The 10 year cause-specific survival rates were 97.2-100%, 91.5-97.4%, and 71.2-80.0%, and 0%, respectively." Kakudo and colleagues published their study in Pathology International (Classification of follicular cell tumors of the thyroid gland: analysis involving Japanese patients from one institute. Pathology International, 2009;59(6):359-67). Additional information can be obtained by contacting K. Kakudo, Wakayama Medical University, Dept. of Human Pathology, Wakayama, Japan. The publisher of the journal Pathology International can be contacted at: Blackwell Publishing Inc., 350 Main St., Malden, MA 02148, USA. Keywords: Japan, Wakayama, Carcinoma Prognosis, Adenocarcinoma, Oncology, Papillary Cancer, Papillary Carcinoma, Pathology, Thyroid Cancer, Thyroid Carcinoma. This article was prepared by Clinical Oncology Week editors from staff and other reports. Copyright 2009, Clinical Oncology Week via NewsRx.com.
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