Penile Cancer
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New penile cancer research has been reported by J.A.P. Leijte et al
2009 MAY 11 - (NewsRx.com) -- "Accurate tumor staging is essential in the management of malignancies. It provides a guide in selecting accurate treatment and gives an indication of prognosis based on the extent of disease," scientists in Netherlands report. "The current TNM classification for penile carcinoma has remained unchanged since 1987. In this article, we focus on several deficiencies of the current classification. An analysis of the current literature regarding the current classification was done, focusing on known prognostic factors for survival. Furthermore, we discuss in detail the results from a recent analysis of more than 500 patients treated at our institute to evaluate the practical and prognostic value of the TNM-classification. We found that, using the current classification system, accurate clinical staging is often difficult, because the T and N categories are defined by structures that are not easily identified using physical examination or imaging. Furthermore, the prognostic stratification of the present staging system is not optimal and there is a substantial overlap in disease-specific survival between several categories. We give an overview of modifications that could improve clinical staging and prognostic ability. The current TNM classification for penile carcinoma has several shortcomings in terms of usability in clinical staging and prognostic value," wrote J.A.P. Leijte and colleagues. The researchers concluded: "With modifications clinical staging is facilitated, while the prognostic stratification of the classification is improved." Leijte and colleagues published their study in World Journal of Urology (Shortcomings of the current TNM classification for penile carcinoma: time for a change' World Journal of Urology, 2009;27(2):151-154). For more information, contact S. Horenblas, Antoni Van Leeuwenhoek Hospital, Netherlands Cancer Institute, Dept. of Urology, Plesmanlaan 121, NL-1066 CX Amsterdam, Netherlands. Publisher contact information for the World Journal of Urology is: Springer, 233 Spring St., New York, NY 10013, USA. Keywords: Netherlands, Penile Cancer, Carcinoma, Men's Health, Neoplasms, Oncology, Urology. This article was prepared by Clinical Oncology Week editors from staff and other reports. Copyright 2009, Clinical Oncology Week via NewsRx.com.
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