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New gynecology data have been reported by R. Usui and co-authors
2009 JUN 29 - (NewsRx.com) -- In this recent study, researchers in Tochigi, Japan conducted a study "To identify risk factors for a short interval to birth in women with preterm labor, and to construct a statistical model to predict birth within seven days from the diagnosis of preterm labor at 22-35 weeks of gestation. Vaginal flora was obtained from 126 singleton pregnant women hospitalized for preterm labor at 22-35 weeks' gestation." "The amount of vaginal large Gram-positive rods (GPR) was counted in a bright field under X400 magnification and classified semiquantitively as loss of GPRs, decreased GPRs (<10), and normal flora (10 or more). The effects of vaginal GPRs, cervical dilatation, and previous history of preterm birth on the subsequent occurrence of birth were analyzed using proportional hazards model, and the effects on birth within seven days from the diagnosis of preterm labor were analyzed using multivariate logistic regression. Fifty-four women (42.9%) delivered preterm. Both loss of GPRs and decreased GPRs were independent risk factors for a short interval from threatened preterm labor to birth, after adjusting the effect of cervical dilatation and past history of preterm birth (hazard ratio 3.4 [95% CI 2.0-5.5] and 2.0 [95% CI 1.1-3.6], respectively). Cervical dilatation of <4.0 cm and 2.0-3.9 cm, and past history of preterm birth were also independent risk factors for a short interval to birth. Loss of GPRs and decreased GPRs, and cervical dilatation of <4.0 cm and 2.0-3.9 cm were independently associated with birth within seven days from the diagnosis of preterm labor (OR 26 [95% CI 5.3-130], 11 [1.9-69], 76 [8.0-720], and 6.4 [1.5-27], respectively)," wrote R. Usui and colleagues. The researchers concluded: "Loss of GPRs and decreased GPRs may be independently important for developing birth in women with preterm labor." Usui and colleagues published their study in the Journal of Perinatal Medicine (Statistical model predicting a short duration to birth in women with preterm labor at 22-35 weeks' gestation: the importance of large vaginal Gram-positive rods. Journal of Perinatal Medicine, 2009;37(3):244-250). For additional information, contact A. Ohkuchi, Jichi Med University, Dept. of Obstetrics & Gynecology, School Medical, 3311-1 Yakushiji, Shimotsuke, Tochigi 3290498, Japan. Publisher contact information for the Journal of Perinatal Medicine is: Walter de Gruyter & Co., Genthiner Strasse 13, D-10785 Berlin, Germany. Keywords: Japan, Tochigi, Gynecology, Perinatal Medicine. This article was prepared by OBGYN & Reproduction Week editors from staff and other reports. Copyright 2009, OBGYN & Reproduction Week via NewsRx.com.
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