Radius Fracture
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Studies in the area of radius fracture reported from Harvard University
2009 JUN 1 - (NewsRx.com) -- According to a study from the United States, " To compare healing rates of distal radius fractures in patients on bisphosphonate therapy at the time of injury to rates in those not on bisphosphonate therapy. A total of 196 consecutive patients treated for distal radius fractures were included in this study." "Patients currently on bisphosphonate therapy at the time of injury (bisphosphonate group, n = 43) were compared to the remaining patient group (control group, n = 153). Demographic information was recorded from the patients' medical records, and radiographs were reviewed to determine fracture healing. Patients were further stratified according to age, gender, fracture complexity, type of treatment, and comorbidities. Univariate and multivariate regression were used to identify factors associated with time to radiographic fracture union. The mean time to union was 55 (+/- 17) days in the bisphosphonate group versus 49 (+/- 14) days in the control group. Bisphosphonate use and surgical treatment were associated with a longer time to radiographic union. Bisphosphonate use was associated with increased healing times when individually controlling for age, gender, fracture complexity, or comorbidities. Bisphosphonate use was also associated with longer time to healing after adjusting for age, gender, and treatment type. Surgical fracture fixation was associated with a longer time to healing after adjusting for bisphosphonate use. Current bisphosphonate use and surgical treatment were both associated with longer times to radiographic union of distal radius fractures. However, the small differences in healing times (< 1 week) are not considered clinically relevant. Although further studies are needed to better define the effects of bisphosphonate therapy on fracture healing, our results suggest that bisphosphonate therapy can be continued after distal radius fractures without notable deleterious effects. (J Hand Surg 2009;34A:595-602," wrote T.D. Rozental and colleagues, Harvard University. The researchers concluded: "Copyright C 2009 by the American Society for Surgery of the Hand. All rights reserved.)'." Rozental and colleagues published their study in the Journal of Hand Surgery - American Volume (Comparison of Radiographic Fracture Healing in the Distal Radius for Patients on and off Bisphosphonate Therapy. Journal of Hand Surgery - American Volume, 2009;34A(4):595-602). For more information, contact T.D. Rozental, Harvard University, School Medical, Beth Israel Deaconess Med Center, Dept. of Orthopedic Surgery, 330 Brookline Avenue, Stoneman 10, Boston, MA 02215, USA. Publisher contact information for the Journal of Hand Surgery - American Volume is: W B Saunders Co-Elsevier Inc., 1600 John F Kennedy Boulevard, Ste. 1800, Philadelphia, PA 19103-2899, USA. Keywords: United States, Boston, Clinical Trial Research, Osteoporosis, Radius Fractures, Surgery, Therapy, Treatment, Harvard University. This article was prepared by Biotech Business Week editors from staff and other reports. Copyright 2009, Biotech Business Week via NewsRx.com.
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