Studies conducted at C.W. Ang et al on reactive arthritis recently published
2007 OCT 8 -- "Weeks or months following Campylobacter infection, a small proportion of infected individuals develop Guillain-Barre syndrome (GBS) or reactive arthritis (ReA). Stool culture for Campylobacter is often negative in these patients, and serology is therefore the method of choice for diagnosing a recent infection with Campylobacter," scientists in Netherlands report. "This study developed a capture ELISA system to detect anti-Campylobacter IgA and IgM antibodies indicative of a recent infection. The sensitivity of the assay was 82.0% in uncomplicated Campylobacter enteritis patients, 96.2% in GBS patients who were culture-positive for Campylobacter, and 93.1% in culture-positive ReA patients, with a specificity of 93.0%," wrote C.W. Ang and colleagues. The researchers concluded: "The assay allows identification of Campylobacter infection in patients with post-infectious neurological and rheumatological complications." Ang and colleagues published their study in Clinical Microbiology and Infection (Validation of an ELISA for the diagnosis of recent Campylobacter infections in Guillain-Barre and reactive arthritis patients. Clinical Microbiology and Infection, 2007;13(9):915-922). For more information, contact C.W. Ang, Academy Med Center, Dept. of Med Microbiology, POB 22660, NL-1100 DD Amsterdam, Netherlands. Publisher contact information for the journal Clinical Microbiology and Infection is: Blackwell Publishing, 9600 Garsington Rd., Oxford OX4 2DQ, Oxon, England. Keywords: Netherlands, Campylobacter, Clinical Microbiology, Diagnosis, Diagnostics, Guillain-Barre Syndrome, Reactive Arthritis, Rheumatology. This article was prepared by Pain & Central Nervous System Week editors from staff and other reports. Copyright 2007, Pain & Central Nervous System Week via NewsRx.com.
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