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New life sciences research from University College described
2009 JUN 30 - (NewsRx.com) -- According to recent research from Cork, Ireland, "The plant-infecting members of the genus Fijivirus (family Reoviridae) have linear dsRNA genomes divided into 10 segments, two of which contain two substantial and non-overlapping ORFs, while the remaining eight are apparently monocistronic." "However, one of these - namely segment 5 contains a second long ORF (similar to 200+ codons) that overlaps the 3' end of the major ORF (similar to 920-940 codons) in the +1 reading frame. In this report, we use bioinformatic techniques to analyze the pattern of base variations across an alignment of fijivirus segment 5 sequences, and show that this 3' ORF has a strong coding signature," wrote A.E. Firth and colleagues, University College. The researchers concluded: "Possible translation mechanisms for this unusually positioned ORF are discussed." Firth and colleagues published their study in Virology Journal (Analysis of the coding potential of the partially overlapping 3' ORF in segment 5 of the plant fijiviruses. Virology Journal, 2009;6():32). For additional information, contact A.E. Firth, University College Cork, BioScience Institute, Cork, Ireland. Publisher contact information for the Virology Journal is: Biomedical Central Ltd., Current Science Group, Middlesex House, 34-42 Cleveland St., London W1T 4LB, England. Keywords: Ireland, Cork, Life Sciences, Reoviridae, Reovirus, Virology, University College. This article was prepared by Life Science Weekly editors from staff and other reports. Copyright 2009, Life Science Weekly via NewsRx.com.
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