Studies from F. Huet and co-researchers update current data on vaccine
2007 NOV 14 -- "This study aimed at estimating the paediatfic RotaVirus GastroEnteritis (RVGE) burden in children aged up to 5 years, and at evaluating health and economic benefits of a universal infant vaccination with a pentavalent rotavirus vaccine, in France. A decision analytic model was constructed considering a cohort of French children from birth to 5 years old," scientists in Dijon, France report. "In the absence of a universal rotavirus immunisation programme, the model predicts that of every new French birth cohort, 336,738 children would present a RVGE case, which would result in 33,386 hospitalisations, 14 deaths and more than 279,000 work days lost for the parents. The management of these RVGE cases would cost E 63 million to the National Healthcare Payer and would reach up to E 117 million when all indirect costs were included. The introduction of a universal rotavirus vaccination would avoid 249,400 RVGE cases and consequently about 25,700 hospitalisations, 6000 nosocomial infections, 81,200 emergency visits, 39,900 general practitioner or paediatrician consultations, I I deaths and 206,700 parental work days lost. RVGE total costs would be reduced by (sic)47 million for the National Healthcare Payer and by (sic)88 million from the Societal perspective," wrote F. Huet and colleagues. The researchers concluded: "Therefore, a routine universal rotavirus vaccination programme represents an opportunity to significantly reduce the high paediatric RVGE burden in France." Huet and colleagues published their study in Vaccine (Burden of paediatric rotavirus gastroenteritis and potential benefits of a universal rotavirus vaccination programme with RotaTeq((R)) in France. Vaccine, 2007;25(34):6348-6358). For additional information, contact F. Huet, Hopital Bocage, Service Pediatrics, 10 Blvd. Marechal Lattre Tassigny, F-21000 Dijon, France. The publisher's contact information for the journal Vaccine is: Elsevier Science Ltd., the Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. Keywords: France, Dijon, Life Sciences, Pediatrics, Vaccine. This article was prepared by Vaccine Weekly editors from staff and other reports. Copyright 2007, Vaccine Weekly via NewsRx.com.
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