Rotavirus Vaccine


Studies from University of Texas in the area of borne disease prevention described



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This article was published in Biotech Business Week, which you can subscribe to online.

2007 NOV 12 -- Fresh data on borne disease are presented in the report 'Advances in defining etiology and new therapeutic approaches in acute diarrhea.' According to recent research from the United States, "Defining etiology of acute diarrhea is critical to disease therapy and prevention. In this review we look at recent developments in etiologic agents of acute diarrhea and advances in therapy and prevention of the illness."

"Newly appreciated agents include enterotoxigenic Bacteroides fragilis, Klebsiella oxytoca and Laribacter hongkongensis. Atypical enteropathogenic E. coli (EPEC) strains lacking the gene for epithelial attachment appear to be more important as causes of diarrhea than traditional EPEC strains. Enterotoxigenic E. coli and enteroaggregative E. coli diarrhea known to be important abroad, have recently been shown to occur in the United States. Non-O157:H7 strains of Shiga toxin-producing E. coli are increasing and infrequently are being sought. There is currently a serious epidemic of nosocomial diarrhea due to a fluoroquinolone-resistant and more virulent and difficult to treat strain of C. difficile. Rotavirus vaccine development should lead to reduction of infant gastroenteritis mortality in infants living in developing regions. Noroviruses produce outbreaks of water-and food-borne disease but show broad genetic diversity. Reduced osmolarity oral rehydration treatment (ORT) and recombinant human lactoferrin/lysozyme plus rice-based ORT effectively treat acute diarrhea. Probiotics were shown to be effective in preventing antibiotic associated-and C. difficile-diarrhea," wrote L.A. Marcos and colleagues, University of Texas.

The researchers concluded: "Rifaximin prevents and azithromycin effectively treats travelers' diarrhea."

Marcos and colleagues published their study in the Journal of Infection (Advances in defining etiology and new therapeutic approaches in acute diarrhea. Journal of Infection, 2007;55(5):385-93).

For additional information, contact L.A. Marcos, The University of Texas, School of Medicine, Houston, TX USA..

Publisher contact information for the Journal of Infection is: W B Saunders Co. Ltd., 32 Jamestown Rd., London NW1 7BY, England.

Keywords: United States, Houston, Borne Disease Prevention, Biotechnology, Borne Disease, Diarrhea, Drug Development, Food Poisoning, Food Safety, Foodborne Disease, Gastroenterology, Immunization, Medical Device, Therapy, Treatment, Vaccination, Vaccine Development.

This article was prepared by Biotech Business Week editors from staff and other reports. Copyright 2007, Biotech Business Week via NewsRx.com.