New sickle cell anemia research has been reported by scientists at Duke University
2007 OCT 29 -- Fresh data on sickle cell anemia are presented in the report 'Fear of movement (kinesiophobia), pain, and psychopathology in patients with sickle cell disease.' "' Fear of movement (ie, kinesiophobia) has emerged as a significant predictor of pain-related outcomes including disability and psychologic distress across various types of pain (eg, back pain, headache, fibromyalgia, complex regional pain syndrome). However, no research has examined the prevalence of kinesiophobia in adults with sickle cell disease (SCD)," scientists in the United States report. "The purpose of this study was to assess the degree of kinesiophobia reported by African American men and women with SCD and to determine whether kinesiophobia is related to pain and psychologic distress in this population. Sixty-seven men and women with SCD recruited from a comprehensive sickle cell treatment program in a large academic medical center completed questionnaires that assess fear of movement, pain and pain interference, and psychologic distress. Participants reported levels of kinesiophobia (M=30.48, SD=7.55) that were comparable to those obtained for patients with low back pain and fibromyalgia. Although pain levels did not differ by sex, men reported greater kinesiophobia than women (p=0.02). As hypothesized, higher levels of kinesiophobia were associated with greater psychologic distress, particularly Phobic Anxiety (r=0.35), Psychoticism (r=0.29), Somatization (r=0.45), Anxiety (r=0.35), Obsessive-compulsive (r=0.34), Interpersonal Sensitivity (r=0.25), Depression (r=0.29), and all 3 summary indices of the SCL-90-R (all Ps <0.05). Although and historically, pain associated with SCD has not been considered in the context of fear of movement, findings suggest that both kinesiophobia and sex are relevant constructs for consideration in understanding pain-related outcomes in SCD," wrote J. Pells and colleagues, Duke University. The researchers concluded: "Though our results require replication, this study suggests that greater kinesiophobia is associated with greater pain and psychologic distress." Pells and colleagues published their study in The Clinical Journal of Pain (Fear of movement (kinesiophobia), pain, and psychopathology in patients with sickle cell disease. The Clinical Journal of Pain, 2007;23(8):707-13). For more information, contact J. Pells, Duke University Medical Center, Dept. of Psychiatry and Behavioral Sciences, Durham, NC 27705 USA.. Publisher contact information for the The Clinical Journal of Pain is: Lippincott Williams & Wilkins, 530 Walnut St., Philadelphia, PA 19106-3621, USA. Keywords: United States, Durham, Hematology, Mental Health, Psychology, Psychopathology, Sickle Cell Anemia, Sickle Cell Disease. This article was prepared by Hematology Week editors from staff and other reports. Copyright 2007, Hematology Week via NewsRx.com.
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