Smallpox Vaccine

Research from Seoul National University, Department of Internal Medicine provide new insights into smallpox vaccines

Smallpox Vaccine Library Library Home This article was published in Pharma Business Week, which you can subscribe to online.

"All subjects achieved positive humoral immune responses (plaque reduction neutralizing antibody assay) 28 days after vaccination, and cell-mediated immune responses (ELISPOT assay) 14 days after vaccination. Humoral immune responses increased up to 28 days after vaccination and were maintained up to 56 days after vaccination," wrote S.H. Kim and colleagues, Seoul National University, Department of Internal Medicine.

The researchers concluded: "In contrast, cell-mediated immune responses increased up to 14 days after vaccination and steadily decreased to 56 days after vaccination [Clinical Trial No. NCT 00336635]."

Kim and colleagues published their study in Vaccine (Detailed kinetics of immune responses to a new cell culture-derived smallpox vaccine in vaccinia-naïve adults. Vaccine, 2007;25(33):6287-91).

For additional information, contact S.H. Kim, Seoul National University Hospital, Dept. of Internal Medicine, Seoul, Republic of Korea.

Publisher contact information for the journal Vaccine is: Elsevier Science Ltd., the Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England.

Keywords: Korea, Seoul, Biotechnology, Immunization, Smallpox Vaccines, Vaccination, Vaccinia Virus.

This article was prepared by Pharma Business Week editors from staff and other reports. Copyright 2007, Pharma Business Week via NewsRx.com.