Stem Cell Research


Studies from Hacettepe University, Division of Pediatric Hematology add new findings in the area of aplastic anemia therapy



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This article was published in Biotech Business Week, which you can subscribe to online.

2007 NOV 19 -- New investigation results, 'Varicella zoster-associated severe aplastic anemia in a child and its successful treatment with peripheral blood stem cell transplantation from HLA-5/6-identical donor,' are detailed in a study published in Medical Science Monitor. According to recent research from Ankara, Turkey, "Varicella zoster virus is very rarely associated with aplastic anemia."

"Bone marrow transplantation from an HLA-identical sibling is the treatment of choice A seven-year-old boy presented with aplastic anemia (AA) following chicken pox infection. No clinical improvement was observed with pharmaceutical therapy and peripheral blood stem cell transplantation (PBSCT) was performed from his HLA 5/6 identical mother," wrote B. Kuskonmaz and colleagues, Hacettepe University, Division of Pediatric Hematology.

The researchers concluded: "Since the transplantation, the patient has had a durable, trilineage hematological response for 12 months The present case with varicella zoster-associated aplastic anemia was non-responsive to conventional therapies (ATG protocol, ALG protocol, oxymethalone, and cyclosporine A) and successfully treated with bone marrow transplantation from his 5/6 identical mother."

Kuskonmaz and colleagues published their study in Medical Science Monitor (Varicella zoster-associated severe aplastic anemia in a child and its successful treatment with peripheral blood stem cell transplantation from HLA-5/6-identical donor. Medical Science Monitor, 2007;13(10):CS128-31).

For additional information, contact B. Kuskonmaz, Dept. of Pediatrics, Division of Pediatric Hematology, Hacettepe University Faculty of Medicine, Sihhiye, Ankara, Turkey.

Publisher contact information for the journal Medical Science Monitor is: International Scientific Literature, Inc., 1125 Willis Avenue, Albertson, NY 11507, USA.

Keywords: Turkey, Ankara, Aplastic Anemia Therapy, Aplastic Anemia, Bone, Chickenpox, Hematology, Pharmaceuticals, Stem Cell Research, Therapy, Treatment, Varicella Zoster, Viral Research, Virology.

This article was prepared by Biotech Business Week editors from staff and other reports. Copyright 2007, Biotech Business Week via NewsRx.com.