New neurocysticercosis study results reported from H.B. Oliveira et al
2009 JUL 28 - (NewsRx.com) -- According to recent research from Uberlandia, Brazil, "The aim of the present research was to test the application of Taenia saginata metacestodes as an alternative antigen for use in enzyme-linked immunosorbent assay (ELISA) and Western Blotting (WB) tests compared with the use of metacestodes antigen of Taenia solium in cerebrospinal fluid (CSF) samples. The samples were obtained from 35 patients with definitive neurocysticercosis (NCC)-group 1-and 44 patients with other neurological disorders (control)-group 2. The sensitivity and specificity of ELISA, using antigen obtained from T. solium, applied to the patients of group 1 yielded results of 100%." "When the tests were conducted using T. saginata metacestodes, results were 100% and 93.2%, respectively. The 47-52-, 64-68-, and 70-kDa antigens showed high frequencies in CSF samples from patients with NCC when WB was conducted with both antigens," wrote H.B. Oliveira and colleagues. The researchers concluded: "The results indicate that T. saginata metacestodes can be used as an alternative antigen for the diagnosis of human NCC in CSF samples." Oliveira and colleagues published their study in Parasitology Research (Saline extract of Taenia saginata metacestodes as an alternative antigen for the immunodiagnosis of neurocysticercosis in human cerebrospinal fluid. Parasitology Research, 2009;105(1):169-174). For additional information, contact H.B. Oliveira, University of Fed Uberlandia, Institute Ciencias Biomedical, Dept. of Imunol Microbiology & Parasitology, Avenue Para 1720, BR-38400902 Uberlandia, MG, Brazil. Publisher contact information for the journal Parasitology Research is: Springer, 233 Spring St., New York, NY 10013, USA. Keywords: Brazil, Uberlandia, Cysticercosis, Neurocysticercosis, Parasitology, Taeniasis. This article was prepared by Life Science Weekly editors from staff and other reports. Copyright 2009, Life Science Weekly via NewsRx.com.
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