New findings from University of Genoa, Medical Department in the area of vaccine described
2009 JUL 14 - (NewsRx.com) -- According to recent research from Genoa, Italy, "Liguria was the first Italian Administrative Region, since 2003, to actively recommend free-of-charge immunisation, of all infants, with heptavalent Pneumococcal Conjugate Vaccine (PCV-7), within a research pilot-project. Vaccination coverage among infants rapidly increased from 42.8% in 2003 to 83.3% in 2004, progressively reaching levels of 93.4% in 2007." "Two scientific projects have been carried Out, aimed: (i) to assess the immunogenicity of PCV-7 and of a hexavalent vaccine Diphtheria-Tetanus-Trivalent Acellular Pertussis-Hepatitis B-Inactivated Polio Virus-Haemophilus influenzae type B (DTaP-HBV-IPV-Hib) when co-administered to healthy infants at 3,5 and 11-12 months of age (routine schedule), and (it) to evaluate the effect of the immunisation campaign in preventing Pneumococcal-associated hospitalisations. in 151 infants showed the high immunogenicity of the vaccines, seroprotection rates, Measured 1 month after the third dose, ranging between 97.3% (serotype 6 B) and 100% (serotypes 4 and 9 V) for PCV-7 and between 99.3% and 100% against common antigens of hexavalent vaccine," wrote P. Durando and colleagues, University of Genoa, Medical Department. The researchers concluded: "Monitoring nearly 70,000 children, aged 0-24 months, during the period 2000-2007, and comparing hospitalisation rates occurred in subjects belonging to birth cohorts before and after the introduction of widespread immunisation, a significant decline for all-cause and pneumococcal pneumonia and for acute otitis media was observed, with preventive fractions of 15.2%, 70.5% and 36.4%, respectively." Durando and colleagues published their study in Vaccine (Universal childhood immunisation against Streptococcus pneumoniae: The five-year experience of Liguria Region, Italy. Vaccine, 2009;27(25-26 Sp.):3459-3462). For additional information, contact P. Durando, University of Genoa, San Martino Hospital, Sect Hyg & Prevention Medical, Dept. of Health Science, Via A Pastore 1, I-16132 Genoa, Italy. Publisher contact information for the journal Vaccine is: Elsevier Science Ltd., the Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. Keywords: Italy, Genoa, Life Sciences, Vaccination, Immunization, Hepatitis B Virus, Virology, HBV, Hepatology, Pediatrics, Gastroenterology, Infectious Disease, Influenza, Flu, Poliomyelitis, Polio Virus, Pneumococcal, Streptococcus, Strep Infection, Streptococcal, Haemophilus, Diphtheria, Whooping Cough, Tetanus, Vaccines, Biotechnology, Pediatric Vaccines, University of Genoa, Medical Department. This article was prepared by Disease Prevention Week editors from staff and other reports. Copyright 2009, Disease Prevention Week via NewsRx.com.
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